Plasma cell-free DNA sequencing assay for advanced prostate cancer
A liquid biopsy assay for predicting survival outcomes of castration-resistant prostate cancer
Stable glutathione analog for the treatment of Alzheimer’s disease
A metabolically stable glutathione analog that resists degradation and offers protection against oxidative stress.
Machine learning algorithm for early prediction of clinical deterioration events
A novel machine learning-based predictive modeling method to predict clinical deterioration events such as (but not limited to) ICU transfer and ventilator use. This enables ‘predictive triaging’, i.e. being able to make triaging decisions hours to days ahead of actual deterioration of a critically ill patient. Factors impacting the deterioration are also explicated, which can be used to prevent the deterioration.
Inhibitors of Cell Adhesion by Nectin Peptides
Peptides that functionally block ovarian cancer cell adhesion by targeting Nectin-4
Self-Supervision via Data Undersampling (SSDU) Software- Evaluation License
Self-supervised physics-based deep learning reconstruction without fully-sampled data for MRI
Hamster CD4 and CD8 antibodies
Monoclonal antibodies against Syrian golden hamster CD4 and CD8
TiW alloy adhesion layer for integration of anodic aluminum oxide on substrates
A method for developing an integrated via structure for improved performance in CMOS applications at millimeter- and submillimeter-wave frequencies
hMETIS Version 1.5
A software package for partitioning large hypergraphs, especially those arising in circuit design.
3D printing of organisms
A 3D printing system with multiple nozzles to automatically pick-and-place single and multiple living organisms in desired 3D locations.
Treating epilepsy via targeted therapy to the endopiriform nucleus (EPN)
A system and method for treating epilepsy and other neurological disorders by deep brain stimulation targeted to the EPN using ultrahigh field MRI.
Pulsed electric field processing of dairy proteins
A method of using pulsed electric field processing to modify functional properties of dairy proteins
Silica-coated polymeric nanoparticles for silicic acid delivery
Novel silica-coated nanoparticles with a stimulus-responsive core that can swell and fracture the surrounding silica shell, leading to the release of silicic acid.
Clarion Grape Variety
Rapid detection and prediction of functional characteristics of dairy powders using near-infrared spectroscopy
A model for predicting the functional properties of dairy powders characterized using NIR spectroscopy
Therapeutic target for treatment of ataxia
A newly identified pathway that represents a therapeutic target for the prevention and treatment of ataxia.
Use of extracellular vesicles to enhance colorectal cancer therapeutics
Cancer-derived extracellular vesicles (EVs) that enhance the efficacy of checkpoint inhibitor therapeutics for colorectal tumors.
Glycoengineered mesenchymal stem cells as targeted therapeutic carriers
A targeted therapeutic delivery system utilizing glycoengineered mesenchymal stem cells for reduced toxicity and increased treatment residence time
An anti-CD133 hybridoma
A hybridoma for manufacturing anti-CD133 antibodies capable of recognizing glycosylated and non-glycosylated epitopes
Hands-free immunoblot washing device
A low-cost, automated method to wash immunoblots
Kudos® Apple Variety
Low-cost laser-induced graphene heaters for polymerase chain reaction
A graphene heater for portable devices with low power consumption and cost of manufacturing
Snowplow Driver-Assist System (DAS)
A novel snowplow driver-assist system that provides lane guidance and forward obstacle detection feedback to snowplow operators when clearing snow in low-visibility conditions.
Machine learning model for ICU management
A machine learning model that uses doctor’s notes for improved prediction of patient condition in ICU settings.
SmartPal: An AI-driven mobile application designed to enhance student engagement
An AI-powered educational companion for enhanced student engagement and performance in instructor-led courses.
Serum-based extracellular vesicle panel for detection for glioblastoma
A blood-based panel for diagnosing and tracking glioblastoma to improve patient outcomes
Hyperstable synthetic miniproteins as ligand scaffolds
Hyperstable synthetic miniproteins as modular ligand scaffolds for advanced therapeutics and diagnostics.
DeepPTx: parallel transmission MRI using deep learning
A novel deep neural network to enhance MRI image reconstruction.
Keratin hydrogels for intravenous embolization
A rapid onset, non-toxic, hybrid hydrogel network for the safe and rapid embolization of blood vessels.
Progesterone receptor detection for breast cancer therapy
A test to detect phosphorylated progesterone receptors for patient stratification
CDK2 inhibitors for cancer therapy and male contraception
CDK2 inhibitors for cancer therapy and non-hormonal male contraception with high selectivity and reduced side effects.
Method for Phase Control in Distributed Arrays
A method of phase alignment in large antenna arrays to improve scalability with low power consumption
Realization of a perfect light absorber in two-dimensional homobilayer by reducing interlayer interaction
Nanofabrication approaches for realizing perfect light absorbance in two-dimensional homobilayer materials
SSDU software for non-Cartesian trajectories- Evaluation License
Non-Cartesian implementation of a self-supervised physics-based deep learning reconstruction without fully-sampled data
Inverse modeling based approach for land cover mapping
A modeling approach for generating land cover maps for crop growth predictions utilizing satellite images and weather data
An assay for detecting Palmer amaranth DNA in individual and mixed samples
A method and kit for determining whether a sample contains Amaranthus palmeri, a prohibited noxious seed in multiple states, plant material.
Seizure Behavioral Testing Protocol (ROAR)
A standardized seizure behavioral testing protocol (ROAR) for enhanced diagnosis and care during video EEG monitoring.
Inhibitory nucleic acid molecules targeting cyclin D1 mRNA
Inhibition of non-canonical functions of cyclin D1 as a potential therapy for liver diseases.
Mouse model for studying SARS-CoV-2
A gene replacement mouse model incorporating human ACE2 and TMPRSS2 genes for authentic SARS-CoV-2 replication and virus entry studies.
Mysteries of Your Brain - Planetarium Show
Mysteries of Your Brain is a 22-minute planetarium show that takes you on an immersive, animated adventure that explores the intricacies and uniqueness of the human brain.
Broadspectrum potentially therapeutic nanobodies against COVID-19
A class of nanobodies (Nanosota-2, -3, and -4) offering broadspectrum therapeutic potential against COVID-19.
Integrated Acousto-optic Light Beam Steering Device
An acousto-optic device design where the acoustic waves directly scatter and steer optical waves into free space for ranging sensors at low cost and with a small form factor.
Water purification device for the simultaneous removal of heavy metals and organic pollutants
A novel photoelectrocatalysis device that can efficiently remove heavy metals and organic pollutants from water.
Soluble, active DNA cytosine deaminase for use as a research tool
A method to produce soluble DNA cytosine deaminase for assays of potential inhibitors of HIV-1 and as a tool for biotech applications
Image processing technique for improved MRI image fidelity
A novel technique to improve MRI image fidelity via the combination of a denoising and deep learning-based reconstruction.
Ferroelectric graphene varactor
A novel graphene varactor design that incorporates a ferroelectric material as part of the insulator.
Nanorings for cell-mediated drug delivery
Farnesylated chemically self-assembled nanorings that facilitate targeted drug delivery between cells.
Backbone rearrangement of polyesters and polyurethanes
A novel method to modify polyester and polyurethane backbones to change material properties and introduce a handle for degradation.
Artificial gut/absorption simulator for evaluation of drug formulations dissolution
A device and method for simulating a digestive gut to evaluate drug delivery that incorporates simultaneous absorption with dissolution
SWIFT Software for Bruker MRI Systems
Bioderived polymers from dienes for compatibilization and recycling of polyethylene and polypropylene mixed waste
Bioderived block copolymers used for the recycling of polyethylene (PE) and polypropylene (PP) mixed waste.
Free-standing perovskite oxide membranes
A novel method for the synthesis and deposition of perovskite oxide membranes onto a substrate.
Film structure modeling and refinement software: FilmInsight
A novel modeling and refinement software designed to analyze the detailed structure of thin films using X-ray diffraction data.
Outbreak at Watersedge: Interactive Public Health Game
A SCORM version of an e-learning game that can be uploaded to an LMS to introduce learners to the world of public health.
Selective catalytic combustion of hydrocarbons
A novel method for the selective combustion of acetylene in a mixture of other hydrocarbons over a metal oxide catalyst.
Encapsulated supported anaerobic biofilms for enhanced methane production
Encapsulated anaerobic biofilms for treating wastewater and generating desirable products such as methane or hydrogen gas.
Novel Antimicrobial Peptide DGL13K
An antimicrobial peptide DGL13 that exhibits several desirable characteristics for a novel antibiotic.
Efficient CRISPR-based gene editing for stem cells
A CRISPR-based gene editing protocol for induced pluripotent stem cells (iPSCs) with improved editing efficiency and cell survival.
Wearable ultrasound sensors for imaging and sensing
Novel wearable ultrasound transducers designed to integrate real-time imaging, sensing, and treatment functions for application in therapeutics and diagnostics.
Quantitative ultrasound for fatty tissue imaging
A signal processing method to enhance ultrasound imaging of fatty tissue.
Superconducting diode effect in a three-terminal Josephson device
A superconducting quantum device for scalable and gate tunable realization of the Josephson diode effect
Dual frequency RF coil for magnetic resonance imaging
A novel RF resonant coil that can operate at both X-nuclear and proton frequencies.
Neonatal pneumothorax decompression device
A rapidly deployable, self-contained device to evacuate air from the pleural space of a neonate.
Single-cell Integration and DrUg Response PrediCtion (scIDUC)
A computational pipeline that predicts drug response scores for individual cells using single-cell RNA sequencing data.
Medical device for the treatment of Raynaud’s phenomenon
A novel therapeutic device that applies blue light and warmth for the treatment of Raynaud’s phenomenon.
Pharmacological enhancement of CD8 T cell effector function using TEPP46
A clinically viable strategy for preventing mitochondria-mediated T cell exhaustion and enhancing effector T cell function.
First-in-class drug lead candidate (A229) for treating ocular diseases
PPARα agonist, A229, exhibits strong potency and demonstrates efficacy in in-vitro models of diabetic retinopathy.
3D printed flexible OLED displays
A method to fully manufacture OLED displays by 3D printing.
3D printed organ models with integrated sensing capabilities
A method to 3D print patient-specific organ models with tissue-mimicking properties and integrated sensing capabilities.
Bacterial histidine kinase inhibitors for treating Staphylococcus infections
Small molecule bacterial histidine kinase inhibitors that significantly diminish staphylococcal virulence.
3D printed damper on the head gimbal assembly of a hard disk drive
A process to 3D print a damping material on the head gimbal assembly of a hard disk drive to reduce vibrations.
Perovskite oxide membrane growth by hybrid molecular beam epitaxy
A novel method to grow freestanding perovskite oxides on 2D materials.
Novel metal-bound heteroarynes for small molecule synthesis
A novel method for the streamlined synthesis of pharmaceutically relevant small molecules via 5-membered metal-bound heteroarynes.
Catheter to measure intra-arterial pressure gradients
A catheter coated in carbon nanotubes and pressure membranes that measures intra-arterial pressure changes.
Small molecule inhibitors for treating alcoholic hepatitis
Bromodomain inhibitor, UMN627, reduces inflammation in mice models of alcoholic hepatitis.
Novel biliary stent and deployment device
A novel device for managing difficult strictures of the pancreatic and biliary ducts.
InTERACCT Program: Occupational health and safety training
Training courses for occupational health and safety workers aimed to equip them to handle risks associated with emerging technologies.
A catheter-based intravenous respirator
A device for direct gas exchange with the venous system to deliver oxygen and support critically ill patients.
Device to deliver large volumes of oxygen intravenously
A device for infusing large volumes of oxygen directly into the bloodstream via an oxygenated and pressurized saline solution.
Lake water quality monitoring using satellite imagery
A method to process satellite imagery to create surface water clarity maps for large geographical areas.
T Cell Receptor Exchange (TRex) Mice
A mouse model for studying physiological antigen-specific T cell behavior.
Infrared photodetector utilizing coaxial nanoaperture antennas
An infrared photodetector utilizing coaxial nanoaperture antennas that enhance photodetection capabilities.
Ovarian cancer prognostic test for predicting response to chemotherapy and bevacizumab
A prognostic molecular test for predicting ovarian cancer patient response to platinum-based chemotherapy and/or treatment with bevacizumab.
The Data Remanence Technique for enhanced data encryption
A data remanence based approach for reliable key extraction from SRAM memory cells.
Highly fluorinated compounds for magnetic resonance-based temperature sensing
Novel fluorinated molecules for temperature sensing by MRI thermometry.
Machine learning model to mitigate the spread of false information on social networks
A machine learning model to identify and classify misinformation spreaders on social networks.
Psychological First Aid: A Community Supported Model E-Learning Module
A SCORM version of an e-learning module that can be uploaded to an LMS to educate learners on the concepts and applications of psychological first aid.
Bisubstrate inhibitors for treating SARS-CoV-2 infections
Bisubstrate inhibitors that target the active site of SARS-CoV-2 Nsp14 methyltransferase (MTase) for treating SARS-CoV-2 infections.
Biomass microbeads for personal care consumer products
Biodegradable microbeads made from unmodified biomass for use in personal care products and cosmetics.
Autonomous wheel loader control system
A new control system architecture to automate the control of a wheel loader.
Nanoscale carbon dots for PFAS phytoremediation
A method for the phytoremediation of PFAS from contaminated soil using carbon-based nanoparticles.
Phytoremediation of PFAS with ultraporous silica nanoparticles
A method for the phytoremediation of PFAS from contaminated soil using ultraporous mesostructured silica nanoparticles.
Reduced complexity modular polynomial multiplication for R-LWE cryptosystems
A method for integrating modular reduction into Karatsuba polynomial multiplication, used to optimize performance of R-LWR-based ciphers and other cryptographic systems.
Early detection of ovarian cancer using a multiprotein classifier
A blood test for detecting ovarian cancer with over 90% accuracy by monitoring key protein levels.
Personalized Online Self-Learning System (POSLS™)
A set of machine learning algorithms to enable hyper personalization of online learning.
Novel compounds for treatment of neurodegenerative disease and chronic pain
Novel alpha2-adrenergic agonists with neuroprotective and/or analgesic properties.
First-generation degraders for class I bromodomain-containing proteins
A bromodomain-targeting degrader of CECR2, an epigenetic regulator that drives cancer metastasis.
Algorithm for registering prostate imaging data
A semi-automatic image registration algorithm that performs registration of prostate multiparametric magnetic resonance imaging (mpMRI) data.
Rubato4Rubato: A software platform for analyzing rubato
A software platform that introduces a new mathematical language to aid musicians, composers, and researchers in exploring and analyzing rubato.
Mars: The Ultimate Voyage (Planetarium Show)
A 25-minute planetarium show that highlights NASA research and training initiatives that are preparing the next generation of astronauts who will head to Mars.
Statewide Work Zone Information System (SWIS)
A real-time database of active, planned, and historical work zones that automatically ingests official traffic control plans to define work zone and traffic control layout.
Dual use fungi to remediate groundwater oil contamination and/or enhance oil and gas recovery
A method utilizing fungal hyphae to degrade non-aqueous liquid phase in contaminated soil and groundwater systems.
Fundamentals of Disability Accommodations and Inclusive Course Design
An online course for instructors that provides foundational knowledge on reducing barriers in the learning environment through disability accommodations and inclusive course design.
Endotracheal intubation with computer vision
A machine learning-based intubation tube for autonomous or computer-assisted endotracheal intubation.
NOD-2-active carboxamide compounds as vaccine adjuvants
Benzimidazole-thiophene carboxamide compounds with NOD-2 agonist activity as potential vaccine adjuvants.
Routine Anti-Racist Conversations for Early Childhood (R.A.C.E.) Worksheet
An educational tool that explains how to talk about race and ethnicity to children based on their developmental stages.
Lentivirus for keratinocyte immortalization and immortalized keratinocyte cell lines
A lentivirus for immortalizing human keratinocytes and immortalized keratinocyte cell lines.
High-throughput screening assay for sickle cell disease drug discovery
A high-throughput screening assay for discovering small molecules that directly inhibit sickle hemoglobin oligomerization.
Self-Efficacy to Reduce Sedentary Behavior (SRSB) Questionnaire
A 9-item questionnaire designed to evaluate self-efficacy to reduce sedentary behavior.
Fixation of nitrogen from renewable resources using non-thermal plasma
A system that fixates nitrogen from air and water to produce nitrate-rich liquids using non-thermal plasma-assisted catalytic reactions.
Autonomous high-accuracy analysis of prostate cancer biopsies
A framework for automated detection of prostate cancer on histopathology slides.
Conditional DUXC knockout mouse model
A conditional DUXC knockout mouse model for use as a basic research tool.
Direct elution caps for reducing autosampler cross-vial contamination
A screw cap that interfaces a pipette tip and autosampler vial, creating a sturdy connection and an elevated pipette tip position within the vial.
Fast 3-dimensional reciprocal space imaging with laboratory X-ray diffraction: RSLab
A software that adds fast 3D reciprocal space imaging capabilities to laboratory X-ray diffractometers with 2D detectors.
Mouse-derived FSHD muscle cell lines
Primary skeletal muscle cell lines isolated from DUX4 expressing FSHD mice.
Generating teratoma-derived skeletal muscle stem cells
A method for generating teratoma-derived skeletal muscle stem cells with functional regenerative capacity.
Small molecules with antiproliferative activity against pancreatic cancer cells
Small molecules that show antiproliferative activity against the pancreatic cancer cell line MiaPaca-2.
Genetically modified endophyte with biofertilizer potential
A genetically modified bacteria (G. diazotrophicus) that is an established plant endophyte and releases high amounts of ammonium when grown on simple sugars
Taconite based pothole and road repair material (Road Patch)
A fast-setting road repair material comprising magnetite, phosphoric acid and appropriately sized aggregate material developed to address the needs of aging infrastructure.
Development of High Gain and High Aperture Efficiency Virtual Element Arrays
A Fabry-Perot Cavity Antenna (FPCA) consisting of a source antenna and a Frequency Selective Surface (FSS) to increase aperture efficiency and antenna gain
Rapid non-invasive portable system for monitoring deterioration of plastics
A system comprising a portable device and image processing software for superficial non-destructive determination of plastic deterioration
Steerable magneto-photonic particles for targeted delivery and collection of light
An embeddable magneto-photonic microparticle that can be externally positioned and orientated for targeted delivery and collection of light.
Fault Detection Technique for Inverter controls
A Control scheme in inverter-based resources (IBR) to simulate synchronous machines in unbalanced faults.
Small molecules promoting differentiation/maturation of stem cell-derived myogenic cells
A combinatorial small molecule treatment that promotes differentiation and maturation of myotubes derived from pluripotent stem cells.
Real-time online Cetane number estimation in jet fuels
A method to prevent in-flight engine failure due to fuel variation. The method employs real-time online Cetane number estimates of jet fuels used by compression ignition engines to enable control of engine performance.
A novel Vertical Axis Wind Turbine (VAWT)
A novel Vertical Axis Wind Turbine well-suited for urban, suburban, and exurban areas
Engineered bacteria for the synthesis of a biodegradable polymer coating
Genetically modified bacteria for the synthesis of a biodegradable polymer to coat fertilizer pellets, allowing nitrogen to be slowly released over time.
Electric-hydraulic conversion machine for off-road vehicle electrification
A new type of electric-hydraulic conversion machine that integrates the rotor of an electric machine with a hydraulic pump and is useful for electrification of off-road vehicles intended for use in construction.
AgRP-Derived melanocortin-5 receptor peptide antagonists
AgRP derived scaffolds composed of natural (Tyr, Ala, Val, Asn) and unnatural amino acids (Dap) with antagonist activity at the mouse MC5R
Negative Bias Temperature Instability aware digital low-dropout regulator
A negative bias temperature instability (NBTI) aware digital low-dropout regulator (DLDO) which utilizes a novel unidirectional shift register for power transistor array control.
Surface Coating with Novel Antimicrobial Peptide DGL13K
Family of antimicrobial peptides, based on the core peptide GL13, that directly attack the bacterial cell membrane.
Low Cost Sorting Network Circuits using Unary Processing
A novel area and power-efficient approach for hardware implementation of sorting network circuits based on “unary processing”
Scale of Alopecia Areata Distress (SAAD)
A tool (e.g., scale) for assessing the psychosocial impact of Alopecia Areata/Totalis/Universalis on patients' lifes.
College of Liberal Arts Career Readiness Tools and Resources
The University of Minnesota-College of Liberal Arts is providing access to a suite of tools and resources specifically designed to support the unique career needs of liberal arts students to help them understand and articulate how their education gives them a career advantage.
Estimation of In-Cylinder Pressure and Combustion Variables from Non-Intrusive External Sensors in a Diesel Engine
Non-intrusive estimation of in-cylinder pressure in diesel engines by using a differential equation algorithm.
Automatic Evaluation of Wheat Resistance to Fusarium Head Blight Using Dual Mask
A method that enables the rapid recognition of wheat spikes and the fungus Fusarium Head Blight diseased areas in wheat.
Synthesis and functionalization of polymers from biomass-derived levoglucosan
Synthesis & functionalization of sustainable polymers with tailored properties from levoglucosan via facile cationic ring-opening polymerization (cROP)
Structured Deterministic Model (SDM 2.0)
An Excel-based, user-friendly tool for estimating airborne concentrations that represent potential occupational inhalation exposure to volatile and semi-volatile chemicals and chemical mixtures, aerosols, particulates, and fibers.
Apparatus and method for tuning the permittivity of ultrahigh dielectric constant materials in an RF coil for MR imaging
Tunable ultrahigh dielectric constant ceramics to significantly improve RF coil efficiency, detection sensitivity, and imaging signal-to-noise ratio in magnetic resonance systems
Self-navigation to enable efficient 3D DWI SE-EPI multi-slab multi-band imaging
A method for correcting MRI data from corruption due to physiological changes.
PV-SMaRT Solar Farm Runoff Calculator Version 3.1
An innovative spreadsheet-based runoff calculator to estimate stormwater runoff from ground-mounted solar photovoltaic sites for pre-construction as well as post-construction site-specific conditions.
A method of improving the efficiency of axial-piston hydraulic motors
A method of improving the energy efficiency of a hydraulic motor by rotating a valve cam for variable piston stroke
High efficiency pump & motor utilizing partial stroke piston pressurization
Novel hydraulic valving system featuring high efficiency variable displacement hydraulic pumps, which can be combined with a variety of existing mechanical piston pumping and/or motoring systems, including radial piston pumps, axial piston pumps, and slider-crank pumps
Method and devices for detection of suspended nanoparticles
An image detection approach that can detect suspended particles much smaller than the wavelength of visible light, or far below the microscope resolution or the diffraction limit of light, using an image sensor.
3D-printed skin-wearable photodetector device
Fully 3D-printed flexible skin-wearable device for real-time measurements of UV-visible exposures.
The Mindful Movement for Physical Activity (MMPA) Program
An eight-week, research-tested mindful physical activity educational program
The Keys to Health & Wellbeing Program (KHW) for adults 50+ years of age
An eight-week, research-tested health & wellbeing educational program for adults over 50
Long-stroke rolling diaphragm cylinder for passive hydraulic rehabilitation robot
Novel fabric-elastomer long-stroke rolling diaphragm (LSRD) cylinder displaying low friction and zero leakage for small and passive hydraulic systems.
Feed-forward XOR physical unclonable functions
Feed-forward XOR physical unclonable functions for device authentication software security
Extrusion via self-lubricated photopolymerization for manufacturing and self-growing robots
A self-lubricated photopolymerization extrusion method for continuous production of profiled polymer parts, which can be deployed in self-growing robots capable of executing a range of tasks, including exploration, burrowing, and traversing tortuous paths.
Method to produce pea protein with improved functionality
A novel method to produce soluble pulse proteins with longer shelf-life that features a clean label and does not compromise nutritional value.
Minnesota Assessment of Pharmacogenomic Literacy (MAPL™)
A questionnaire to assess pharmacogenomic knowledge among patients in research studies or clinical care.
Rapid carbon-free iron ore reduction with high-density hydrogen plasma
A new method of using hydrogen plasmas for rapid and carbon-free iron ore reduction using micron and submicron-sized iron ore particles.
High performance, highly efficient valves for controlling gas flows
A disruptive pneumatic proportional valve technology has been developed that replaces traditional solenoid actuators with piezoelectric actuators. The valves offer two order of magnitude reductions in power consumption, making them ideal for portable applications. They match the flow capacity of most miniature pneumatic valves. They offer highly linear control regardless of operating pressure. They are the fastest of any available pneumatic valves.
Methods for Modifying Proteins and Peptides.
Production of alpha-N-methylated peptides for improved pharmacological properties.
Human Myotonic Dystrophy Induced Pluripotent Stem Cell Lines
Treating trauma-induced acute blood loss
Novel formulations of D-β-hydroxybutyrate and melatonin improve survival from hemorrhagic shock.
Pain therapy without the risk of respiratory depression, addiction or abuse
An analgesic combination of peripherally restricted opioids that eliminates the risk of respiratory depression, chemical addiction or abuse.
Medical Device for Chronic Sinusitis
The technology is a design of a medical device that can be placed in the ostium between the maxillary sinus and nasal passageway for treatment of chronic sinusitis.
HUH fusion enzymes for multiplex protein labeling
HUH fusion tags are novel, robust endonucleases that allow proteins and DNA to be linked covalently in one simple step
Cell-free selection of site-specific polypeptide binders via tethering
In vitro selection method for the engineering of protein-based high-affinity binders to targets of interest with potential pharmacological value
Compound with selective inhibition potential against P300 and CBT
A compound to treat pediatric sarcoma through the inhibition of P300 and CBT
Live cell assay to quantify the activity of SARS-CoV-2 main protease, Mpro
Fluorescence-based method to effectively screen for protease inhibitors
Camelid single domain antibody phage display library
Highly diverse camelid antibody phage library to screen for binders to nearly any molecular target
A data privatization method which maintains statistical accuracy
A novel data protection method that maintains the statistical accuracy of the data and also provides state-of-the-art data privacy.
T cell receptors for engineered T cell therapy
Mesothelin-specific T cell receptors for cell engineering and cancer therapy
UEMview: Source files for UEM delay stage and detector communication
Software files for automating image acquisition in TEM
A process to make ultra-high purity urea at low cost by using enzymes
Low cost enzyme-processed ultra-high purity urea for high-grade fertilizer, diesel emissions fluid and pharmaceuticals
Enhancement of dynamic wireless communication system speed and performance using continuous learning
An approach that enables data-driven methods to continuously learn and optimize resource allocation strategies in dynamic environments of wireless communications.
Hydraulic switch-mode power transformer for wave powered desalination plants
Efficient hydraulic power-take-off circuit for wave-powered reverse osmosis desalination plants that independently controls the load on the wave energy converter and the pressure at the reverse osmosis membrane through a switching valve
Nanominne-1: novel virus-like particle (nanoparticle) vaccines to prevent SARS-CoV-2 infections
Series of novel vaccines containing 60 copies of SARS-CoV-2 antigens displayed in ordered array on a virus-like particle scaffold (nanoparticle)
Targeted Artificial DNA Replisome (TADR) a Tool for Targeted Mutagenesis
TADR is a protein-complex designed to target and mutate specific genes on plasmid in vivo
Augmented reality transjugular intrahepatic portosystemic shunt (AR-TIPS) set and other interventional devices
An augmented reality (AR) system to assist clinicians in performing medical procedures inside the body where 3D anatomical information is important
Immortalized clonal human myoblast line "M007"
Immortalized human myoblast cell line obtained from a healthy individual
Immortalized clonal human fibroblast line "F007"
Immortalized human fibroblast cell line obtained from a healthy individual
Electron paramagnetic resonance (EPR) imaging without magnet
A method which produces low cost EPR imaging with better receiver isolation and no magnet requirement
Engineered SARS-CoV-2 spike ectodomain for COVID-19 diagnostic assays
Engineered SARS-CoV-2 spike ectodomain expressed from stably transfected mammalian cell lines to be used as an effective diagnostic antigen against different SARS-CoV-2 variants
A system for unattended delivery of cognitive neuromodulation therapy
Non-invasive interactive system with specialized equipment and customizable stimulation unit to deliver unattended cognitive neuromodulation therapy. The system supports training of prescribers and clinical staff leading to certification
Method for mass production of high performance magnetic nanoparticles for biomedical applications
Iron nitride nanoparticles are post-processed by applying a wet ball milling method in conjunction with different surface-active media and centrifugation steps to obtain ultra-stable, monodispersed, uniformly sized, surface-functionalized, and sub-100-nm iron nitride nanoparticles suitable for biomedical applications
Functionalized filters for high efficiency bioseparation
A bioseparation device using a novel filter to facilitate collection and extraction in large volumes and at high flow rates.
3D printable bovine head model
Kidney and Kidney Tumor Segmentation Data
High resolution CT images of kidneys for training machine learning algorithms.
Epoxy resins with improved toughness
A composite material made of epoxy combined with graphene and block copolymer for improved toughness.
AGRP-derived melanocortin receptor ligands
Identifying a selective MC4R antagonist for appetite modulation
Chimeric melanocortin receptor ligands
Melanocortin-4 receptor ligand reduces food intake in mice
Selective melanocortin receptor ligands
Potential dual-ligand approach to weight management
Lateral flow assay for respiratory viruses
CRISPR/Cas9-based point-of-care diagnosis for SARS-CoV-2
Modular convection-enhanced evaporation (CEE) system for brine management
An energy efficient modular convection-enhanced evaporation (CEE) system and control algorithm for brine management
Electrical-field bidirectional switching of full MTJs
A full MTJ stack device with bidirectional magnetization switching purely through an electric field
SHE-CRAM: Computational Random Access Memory (CRAM) based on Spin Hall Effect
Spintronics-based memory array system that performs true in-memory computational operations. The novel spin Hall effect (SHE) technology is used to implement a new CRAM computer architecture (SHE-CRAM) that is capable of inter-raw communication
Efficient graphene acoustic plasmon resonator
A graphene-based device for ultrasensitive infrared spectroscopy and sensing
Just One Thing (JOT): custom care plans for people with cognitive challenges
A simple, customizable clinical care guide and worksheet to promote at-home therapy for people with cognitive challenges and their caregivers.
Sugar-secreting green microalga
A microalgae strain that secretes simple sugars in conditions favorable for co-culture schemes and fermentation processes.
Advanced manufacturing method to fabricate removable partial denture
A series of methods and designs to quickly and accurately fabricate partial dentures from intraoral scanning without stone or printed models. The methods include harnessing the abilities of 3d printing, milling, and scanning technology to allow for the most efficient clinical and laboratory outcomes.
Assisted machine learning architecture
A disruptive machine learning architecture invented for privacy-sensitive entities to collaborate with each other without sacrificing the quality of gained intelligence.
Airless tire with improved performance
A non-pneumatic tire using topological polarization and protection to improve asperity accommodation and tire durability.
Non-toxic plastics containing salicylates
Sustainable polymers containing salicylic acid moieties and a method for their synthesis, enabling enhanced hydrolytic degradability that can promote biodegradability while maintaining important material properties.
Cryopreservation method for millimeter scale biological samples using Cryomesh
A cryopreservation method that uses cryomesh and cryopreservation agents to preserve Drosophila embryos.
Multi-faceted glue for long-term survival of osseointegrated prosthetic devices
A multi-functional photopolymerizable glue that enhances the physical and biological adhesion between soft skin and a metal prosthetic device.
Combined ammonia recuperation and NOX reduction for increased efficiency in combustion engines
A reactor that combines selective catalytic reduction and thermochemical recuperation together to simultaneously decompose ammonia and convert unburned ammonia and NOX emissions
A counter based in-situ non-linearity measurement circuit in analog-to-digital converters
A novel light-weight measurement circuit to characterize non-linearity in analog-to-digital converters.
Risk-free in situ non animal (RISNA) surrogate assay for African swine fever virus
A method of using a surrogate virus to confirm inactivation of African Swine Fever Virus(ASFV)
Rapid infuser purge valve
A one-way purge valve that allows for quick removal of air from IV fluid bags with a single spike.
Network Neuromodulation
A closed-loop deep brain stimulation device that exploits new mechanisms of action to control brain networks
Algorithm to improve left ventricular assist device implantation
An image processing algorithm to determine ideal, patient-specific location parameters for LVAD implantation.
Accelerating MRI data acquisition with segmented 2D pulses
A method for accelerating MRI data acquisition with segmented 2D pulses using virtual coils.
Non-Cartesian k-space reconstruction to improve acquisition efficiency
A non‐Cartesian k‐space reconstruction method using self-calibrated, region‐specific interpolation kernels for highly accelerated acquisitions in MRI.
MRI RF coil for improved field efficiency and image quality
A novel RF coil design with high dielectric constant materials to improve B1+ efficiency in MRI systems.
A hybrid machine learning-based magnetic resonance image reconstruction
A machine learning-based magnetic resonance image reconstruction algorithm that combines the benefits of both linear GRAPPA and nonlinear RAKI methods.
High gyrotropy sputtered garnet for photonic isolators
A design and method to fabricate high-gyrotropic optical isolators directly on Si and other common substrates, without using seed layers. This foundry-friendly technology enables creation of smaller, high performance components.
Automated freeway queue warning system
A system for estimating crash-probabilities for automated freeway warning systems.
Low-energy platinum coatings
A method for low temperature thin-film deposition of high melting point metals, like Pt, and their oxides.
Observability constrained vision-aided inertial navigation (OC-VINS)
Novel techniques for eliminating estimator inconsistency in vision-aided inertial navigation systems.
Urinary Catheter Stabilization Device
A urinary catheter support device that prevents penile erosion arising from the use of indwelling catheters.
Vehicle-weight based automated passenger counter
A system and method for estimating the number of passengers on a mass transit vehicle.
Rapid microbial diagnostics
A method for rapid detection of microorganisms using chemiluminescence.
Autonomous, high accuracy classification of cancer in tissue samples
A machine learning-based algorithm for cancer detection and classification.
PhysiAware - continuous monitoring of physiological signals
An app for continuous monitoring of physiological signals from sensors worn by patients.
Quantitative relaxation mapping
Pulse sequence for MRI scanners
A novel approach for bioprinting complex tissue models
A new method to align cells in muscle tissue using long, pre-aligned microtissues, which are suspended in a bio-ink and printed using a 3D extrusion bioprinter to form larger macrotissues.
Novel anti-cancer agents that target the epigenetic reader protein
Small-molecule inhibitors target the bromodomain and PHD finger transcription factor (BPTF) for development as anti-cancer therapeutics.
HapShared - a software for pedigree reconstruction
A Python script for performing complex pedigree analysis with high sensitivity.
Triumph™ Brand Apples
The latest apple cultivar from the renowned University of Minnesota apple breeding team.
Spin orbit torque generating materials
A novel material with a large spin Hall angle for applications in spintronic devices.
Stochastic computing on pulse-width modulated signals
A low-cost system for computing stochastically using periodic analog signals.
Iterative Kalman smoother for robust 3D localization for vision-aided inertial navigation
A method for tracking 3D motion of a VINS system in real-time.
Chaotic desynchronization of neural populations with non-pulsatile inputs
A method to identify stimulation parameters for desynchronizing a set of neurons.
Software for dual-mode ultrasound array driver and imaging platform (DMUA-DIP)
A software to drive dual-mode ultrasound arrays in imaging and therapy modes in a synchronized fashion.
Utilizing periodic irradiation to enhance sensitivity of magnetic resonance detection
A periodic irradiation method for measuring exchange-induced relaxation rate constants to characterize tissue properties using MR spectroscopy.
Pressure shifted and displacement adjusted valve timing
Methods for adjusting hydraulic pump/motor valve timing.
Central airway stent removal device
A medical device for manipulation and removal of airway stents.
Use of sulfanegen and its analogs for prevention and treatment for neurodegenerative disorders
A 3-mercaptopyruvate prodrug, sulfanegen, that reduces neuroinflammation and oxidative stress for therapeutic use in neurodegenerative diseases.
Minimally invasive diagnostic for osteosarcoma in dogs
A panel of six definitive biomarkers that can be isolated from a canine blood sample for the detection of minimal residual disease and monitoring remission in dogs treated for osteosarcoma.
A method to identify cell-free biomarkers of cancers and other diseases
A cost-effective method to discover biomarkers for a variety of cancers that can be measured in a blood sample and can inform risk, diagnosis, prognosis and predict responses to therapy.
Assessing tumor behavior and response to therapy
A method to identify biomarkers for the detection of tumor behavior and/or increased risk for tumor metastasis in order to improve patient outcomes in both humans and animals.
Machine learning for early cancer detection
A machine learning method to train and validate algorithms to classify cancer risk based on a blood sample.
Wind turbine icing loss forecasting software
A software for forecasting wind turbine performance reduction caused by ice formation.
Control system to optimize wind turbine farm efficiencies
A method to optimize wind turbine farm efficiencies by minimizing performance loss caused by wind veer.
Control system to optimize cold climate wind turbine performance
A method for mitigating wind turbine performance degradation caused by ice formation.
Analgesic and anti-addictive compositions for treatment of chronic pain and opioid addiction
Strategically substituted agmatine derivatives as selective NMDA receptor subunit 2B (NR2B) antagonists for the treatment of chronic pain and opioid addiction.
Remote sensing based classification of soybean aphid-induced stress in soybean
A method for identification of soybean aphid infestation and classification based level of infestation.
Biodegradable elastomers for 3D printing at low temperatures
A method of using a block copolymer comprising PCL and a stretchable amorphous block such as P(βMδVL) or random P(CL-co-DLLA) for creating extruded structures with bioactive ingredients.
High throughput cryopreservation system for up to millimeter-sized samples
A method for cryopreservation of large (100-1000micron dia.) biological samples while improving cell viability.
Detection of toxic small molecules using polymers and Raman scattering
A method to capture one or more analytes using polymers to enable multiplex quantitative detection by surface-enhanced Raman scattering
Community-based antibiotic screening method for polymicrobial infections (2020-090)
An improved antibiotic susceptibility test (AST) that determines minimal inhibitory concentration (MIC) with high physiological relevance for polymicrobial infections.
Fast and reliable neutralization antibodies assay for AAV gene therapy (2020-121)
An assay to measure neutralization antibodies for adeno-associated viral vectors in gene therapy, to screen patients for clinical trials and treatment.
Juicy Jewel™ Brand Pears
An early-ripening Asian-type pear that produces sweet, crisp fruits with yellow-green skin and the occasional orange-pink blush.
Golden Sunset™ Grass
An attractive grass variety with olive-green foliage and yellow-gold flowers.
Device for extracting long genomic DNA from human cells
A microfluidic device for automated cell lysis and extraction of long DNA strands.
Device to Expand Soft Tissue
UEMtomaton: Software for automating image acquisition in electron microscope
Software files for automating image acquisition in TEM
SARS-CoV-2 spike receptor-binding domain for use in COVID-19 assays (2020-301)
Stably transfected mammalian cell lines that express the receptor-binding domain of the SARS-CoV-2 spike protein for use in assays and research relevant to COVID-19 and potential therapies.
Multifunctional, flexible sensor array for urethral catheters (20140233)
A new urethral catheter for simultaneous measurement of pressure distribution and neural activity.
Continuous honey bee cell-line, AmE-711 (2020-240)
The first and only honey bee cell-line available for use in research and experimental testing.
Orthodontic teeth aligners enabling deeper analysis and personalized treatment plans (2020-227, Dr. Alex Fok)
A system and method for measuring stress and strain distribution of invisible orthodontic teeth aligners.
3D Spine Registration Software for Computational Thoracic Volume Modeling (20160071)
Circulating tumor biomarkers for meningiomas (2020-164)
A biomarker panel for early diagnosis of meningiomas with the potential to improve patient outcomes.
Adenovirus Vector Generating System (20110090)
Siderophore-based diagnosis of bacterial infections (20150206)
Vision-aided Inertial Navigation System (VINS) for 3D Ground Vehicle Localization (20180123)
Animal and Agriculture Emergency Response Software Portfolio (20180172)
Social Acuity Game (SAGA) for ASD children (20180167)
Bon App French Pronunciation App (20180165)
MNSight App for Landscape and Geological Data (20180150)
Bone Model Algorithm for 3D in vivo Joint Kinematics (20180008)
Biofeedback Hand Grip Exercise Device for Assessing Muscle Function (20170200)
Autonomous data corruption filter for 3D image reconstruction (20180303)
An autonomous data corruption filter algorithm for recovering 3D structure of an object from 2D images.
Single Thread Large-scale Localization and Mapping (20170194)
A streamlined method to isolate Fibroadipogenic progenitor cells from muscle (2020-195)
A method to isolate fibroadipogenic progenitor cells (FAPs) based on the presence of a single surface marker (CD73).
5G Tracker Android application for collecting and visualizing 5G performance data (2020-287)
An Android and web application to track 5G network performance.
Monoclonal Anti-FAP for cancer research and therapeutic development (2019-131)
A plasmid encoding a recombinant monoclonal antibody against tumorigenic protein FAP in the tumor stroma that is ideal for both basic research and therapeutic drug development.
Antagomir to prevent cardiac arrhythmia (2019-069)
A novel small molecule screening platform for tauopathies (2019-123)
FRET-based biosensors that identify early toxic states of tau for use in basic research and clinical development of therapeutics for tauopathies including Alzheimer’s Disease.
Food Supply Chain Risk Assessment and Mitigation Tools (20180173)
Technology #20180173-20180174-20180175-20180176-20180177-20180178
Active Knit Compression Garment Portfolio (20170290)
A portfolio of shape memory alloy (SMA) functional active knits offers several types of wearable compression garments as well as a novel process for creating them. Technology #20170290-20180107-20180120-20180298
Opioid and Analgesic Chemical Compound Library (z09208)
E. Coli Fermentation of Glycerol from Biodiesel Waste into Ethanol
Functional Analysis of Networks in the Neural System
Organic Photovoltaic Solar Cells using Graded Heterojunction Technology
Photovoltaic Organic Solar Cells using Graded Heterojunctions are Less Expensive and More Efficient
Infection Control System for Sterilization of Catheter Access Points with Ultraviolet (UV) Light
Spectrum Sensing Cognitive Radios
Corn Stover Agglomerates for Oil Absorption
Iron Deficiency Mouse Model
Plasmonic Device Produces Collimated, Monochromatic Light from Heat
Ultra-smooth Patterned Metal Films for Plasmonics
Ultra-smooth Patterned Metal Films for Plasmonics and Metamaterials
High Yield Ammonia Production
Efficiency and Space Improvements in Electrical Apparatus
Compact Power Transformer Design is More Efficient and Less Complex
Power Transformer Design Improves Efficiency
ParMETIS - Mesh Graph Partitioning Algorithm
Improved Impedance Measurements for Pulmonary Edema from Pacemaker or CRT-ICD Leads
Improved Monitoring of Heart Failure Using Bioimpedance
SALSA - Automated Speech Assessment
For Quantitative Neuropsychological Cognitive Assessment