HapShared - a software for pedigree reconstruction
A Python script for performing complex pedigree analysis with high sensitivity.
Triumph™ Brand Apples
The latest apple cultivar from the renowned University of Minnesota apple breeding team.
High-temperature resistant inorganic nanofiber membrane filtration coating material
A one-step, gas phase deposition method to create durable inorganic nanofiber coating on filtration substrates for enhanced filtration performance at high temperatures.
Spin orbit torque generating materials
A novel material with a large spin Hall angle for applications in spintronic devices.
Solvent-free extraction of metal ions from highly toxic aqueous waste streams
A method for generation and use of polymeric capsules for solvent-free extraction of metal ions in applications such as waste remediation, metal recycling, etc.
Stochastic computing on pulse-width modulated signals
A low-cost system for computing stochastically using periodic analog signals.
Iterative Kalman smoother for robust 3D localization for vision-aided inertial navigation
A method for tracking 3D motion of a VINS system in real-time.
Chaotic desynchronization of neural populations with non-pulsatile inputs
A method to identify stimulation parameters for desynchronizing a set of neurons.
Software for dual-mode ultrasound array driver and imaging platform (DMUA-DIP)
A software to drive dual-mode ultrasound arrays in imaging and therapy modes in a synchronized fashion.
Utilizing periodic irradiation to enhance sensitivity of magnetic resonance detection
A periodic irradiation method for measuring exchange-induced relaxation rate constants to characterize tissue properties using MR spectroscopy.
Pressure shifted and displacement adjusted valve timing
Methods for adjusting hydraulic pump/motor valve timing.
Central airway stent removal device
A medical device for manipulation and removal of airway stents.
Use of sulfanegen and its analogs for prevention and treatment for neurodegenerative disorders
A 3-mercaptopyruvate prodrug, sulfanegen, that reduces neuroinflammation and oxidative stress for therapeutic use in neurodegenerative diseases.
Minimally invasive diagnostic for osteosarcoma in dogs
A panel of six definitive biomarkers that can be isolated from a canine blood sample for the detection of minimal residual disease and monitoring remission in dogs treated for osteosarcoma.
A method to identify cell-free biomarkers of cancers and other diseases
A cost-effective method to discover biomarkers for a variety of cancers that can be measured in a blood sample and can inform risk, diagnosis, prognosis and predict responses to therapy.
Assessing tumor behavior and response to therapy
A method to identify biomarkers for the detection of tumor behavior and/or increased risk for tumor metastasis in order to improve patient outcomes in both humans and animals.
Machine learning for early cancer detection
A machine learning method to train and validate algorithms to classify cancer risk based on a blood sample.
Wind turbine icing loss forecasting software
A software for forecasting wind turbine performance reduction caused by ice formation.
Control system to optimize wind turbine farm efficiencies
A method to optimize wind turbine farm efficiencies by minimizing performance loss caused by wind veer.
Control system to optimize cold climate wind turbine performance
A method for mitigating wind turbine performance degradation caused by ice formation.
Analgesic and anti-addictive compositions for treatment of chronic pain and opioid addiction
Strategically substituted agmatine derivatives as selective NMDA receptor subunit 2B (NR2B) antagonists for the treatment of chronic pain and opioid addiction.
Remote sensing based classification of soybean aphid-induced stress in soybean
A method for identification of soybean aphid infestation and classification based level of infestation.
Biodegradable elastomers for 3D printing at low temperatures
A method of using a block copolymer comprising PCL and a stretchable amorphous block such as P(βMδVL) or random P(CL-co-DLLA) for creating extruded structures with bioactive ingredients.
High throughput cryopreservation system for up to millimeter-sized samples
A method for cryopreservation of large (100-1000micron dia.) biological samples while improving cell viability.
Detection of toxic small molecules using polymers and Raman scattering
A method to capture small molecules using polymers for quantitative detection using surface-enhanced Raman scattering.
Community-based antibiotic screening method for polymicrobial infections (2020-090)
An improved antibiotic susceptibility test (AST) that determines minimal inhibitory concentration (MIC) with high physiological relevance for polymicrobial infections.
Fast and reliable neutralization antibodies assay for AAV gene therapy (2020-121)
An assay to measure neutralization antibodies for adeno-associated viral vectors in gene therapy, to screen patients for clinical trials and treatment.
Juicy Jewel™ Brand Pears
An early-ripening Asian-type pear that produces sweet, crisp fruits with yellow-green skin and the occasional orange-pink blush.
Golden Sunset™ Grass
An attractive grass variety with olive-green foliage and yellow-gold flowers.
Device for extracting long genomic DNA from human cells
A microfluidic device for automated cell lysis and extraction of long DNA strands.
Device to Expand Soft Tissue
UEMtomaton: Software for automating image acquisition in electron microscope
Two-step coating method for improved high temperature filtration
A method to create nano-scale membrane coated porous ceramic filtration material to dramatically improve both initial filtration efficiency and soot loading behavior of conventional DPFs/GPFs and filters used in other high temperature applications.
SARS-CoV-2 N-protein for use in COVID-19 serological assays (2020-323)
Full length SARS-CoV-2 Nucleocapsid (N) protein expressed by bacteria for use in serological assays to detect previous COVID-19 infection in humans and animals.
SARS-CoV-2 spike receptor-binding domain for use in COVID-19 assays (2020-301)
Stably transfected mammalian cell lines that express the receptor-binding domain of the SARS-CoV-2 spike protein for use in assays and research relevant to COVID-19 and potential therapies.
Multifunctional, flexible sensor array for urethral catheters (20140233)
A new urethral catheter for simultaneous measurement of pressure distribution and neural activity.
Continuous honey bee cell-line, AmE-711 (2020-240)
The first and only honey bee cell-line available for use in research and experimental testing.
Wearable laryngeal vibration system for Spasmodic Dysphonia (20170400)
A non-invasive neuromodulation device and method for the treatment of spasmodic dysphonia.
Orthodontic teeth aligners enabling deeper analysis and personalized treatment plans (2020-227, Dr. Alex Fok)
A system and method for measuring stress and strain distribution of invisible orthodontic teeth aligners.
High performing ultrafiltration membranes with high selectivity and permeability (2020-370)
A method to fabricate high performance filtration membranes at industrial scale.
Pharmacological agents to prevent recurrent C. diff infection (20150362)
Cholic and bile acid derivatives that inhibit Clostridium difficile spore germination to prevent or treat C. diff infection.
3D Spine Registration Software for Computational Thoracic Volume Modeling (20160071)
Circulating tumor biomarkers for meningiomas (2020-164)
A biomarker panel for early diagnosis of meningiomas with the potential to improve patient outcomes.
Adenovirus Vector Generating System (20110090)
Siderophore-based diagnosis of bacterial infections (20150206)
Vision-aided Inertial Navigation System (VINS) for 3D Ground Vehicle Localization (20180123)
Animal and Agriculture Emergency Response Software Portfolio (20180172)
Social Acuity Game (SAGA) for ASD children (20180167)
Bon App French Pronunciation App (20180165)
MNSight App for Landscape and Geological Data (20180150)
Bone Model Algorithm for 3D in vivo Joint Kinematics (20180008)
SHE-CRAM: Computational Random Access Memory (CRAM) based on Spin Hall Effect (20180422)
Deep Brain Stimulators (DBS) to Treat Glioblastoma (20180080)
A device and method for treating tumors using optimized electromagnetic signals.
Biofeedback Hand Grip Exercise Device for Assessing Muscle Function (20170200)
Autonomous data corruption filter for 3D image reconstruction (20180303)
An autonomous data corruption filter algorithm for recovering 3D structure of an object from 2D images.
Single Thread Large-scale Localization and Mapping (20170194)
A method to genetically engineer monocytes (20180236)
The first and only method available to create genetically modified CD14+ monocytes for use in research or therapy.
A streamlined method to isolate Fibroadipogenic progenitor cells from muscle (2020-195)
A method to isolate fibroadipogenic progenitor cells (FAPs) based on the presence of a single surface marker (CD73).
5G Tracker Android application for collecting and visualizing 5G performance data (2020-287)
An Android and web application to track 5G network performance.
Monoclonal Anti-FAP for cancer research and therapeutic development (2019-131)
A plasmid encoding a recombinant monoclonal antibody against tumorigenic protein FAP in the tumor stroma that is ideal for both basic research and therapeutic drug development.
Antagomir to prevent cardiac arrhythmia (2019-069)
A novel small molecule screening platform for tauopathies (2019-123)
FRET-based biosensors that identify early toxic states of tau for use in basic research and clinical development of therapeutics for tauopathies including Alzheimer’s Disease.
Acceleration of heterogeneous catalysis through dynamic resonance (2019-226)
A method to dynamically vary binding rates to drastically increase rate of chemical reactions involving heterogeneous catalysts.
Food Supply Chain Risk Assessment and Mitigation Tools (20180173)
Technology #20180173-20180174-20180175-20180176-20180177-20180178
Active Knit Compression Garment Portfolio (20170290)
A portfolio of shape memory alloy (SMA) functional active knits offers several types of wearable compression garments as well as a novel process for creating them. Technology #20170290-20180107-20180120-20180298
Opioid and Analgesic Chemical Compound Library (z09208)
E. Coli Fermentation of Glycerol from Biodiesel Waste into Ethanol
Dental Implant Bone Cement for Stabilizing Dental Implants and Bone Osseointegration
Calcium Based Dental Bone Cement for Dental Implant Osseointegration
Functional Analysis of Networks in the Neural System
Organic Photovoltaic Solar Cells using Graded Heterojunction Technology
Photovoltaic Organic Solar Cells using Graded Heterojunctions are Less Expensive and More Efficient
Transforming Air-Ground Miniature Robots
Infection Control System for Sterilization of Catheter Access Points with Ultraviolet (UV) Light
Spectrum Sensing Cognitive Radios
Geothermal Power Generation from Carbon Dioxide Sequestration Uses Renewable Resources
Geothermal Power Generation: Clean Energy from Carbon Dioxide Sequestration
Corn Stover Agglomerates for Oil Absorption
Iron Deficiency Mouse Model
Plasmonic Device Produces Collimated, Monochromatic Light from Heat
Ultra-smooth Patterned Metal Films for Plasmonics
Ultra-smooth Patterned Metal Films for Plasmonics and Metamaterials
High Yield Ammonia Production
Efficiency and Space Improvements in Electrical Apparatus
Compact Power Transformer Design is More Efficient and Less Complex
Power Transformer Design Improves Efficiency
Artificial Cornea Made From Silica Composite
Transgender Films Feature Stories from Transgender Individuals
ParMETIS - Mesh Graph Partitioning Algorithm
Improved Impedance Measurements for Pulmonary Edema from Pacemaker or CRT-ICD Leads
Improved Monitoring of Heart Failure Using Bioimpedance
SMART Signal, Traffic Data Collection for Urban Traffic Flow
Web Based Video Annotation Tool
SALSA - Automated Speech Assessment
For Quantitative Neuropsychological Cognitive Assessment
Organic Photovoltaic Portfolio
Increased Organic Photovoltaic Efficiency
Transposon Induction of Glioma Brain Tumors and Cancer Stem
The Savvy CaregiverTM Program for Alzheimer Caregiver Training
Uncooled Infrared Detectors with High Sensitivity
High Sensitivity Mid-wave Infrared Thermal Sensor
Stair Climbing Robot for Military and Security Applications
Account Reporting Tool for Completing Financial Reports
Ultrathin Zeolite Production Method
Post-Viterbi Error Correction based on Syndrome Value
Ritonavir Analog with Anticancer Activity
Biodegradable Polylactide Polymer from Polymerized Oil
MRI Contrast Software Based on RAFF-n
High-Precision Vehicle Navigation using Kalman Filter Algorithm
Ammonia Production without Molecular Hydrogen for use in Fertilizer Production
Bactericidal Lanbiotic Inhibits Gram-negative Bacteria
CDesK© - Modular Desk / Workstation Design and Manufacturing Specifications
Syncope Warnings with Minimally Invasive Medical Device for Monitoring Blood Flow
Monitoring Blood Flow and Predicting Syncope with Minimally Invasive Medical Device
Biosynthesis of Biodiesel without Glycerin By-Product
Nanostructured Membranes for Gas and Liquid Separation
Cellulosic Ethanol Production from Starch or Cellulose Derived Sugars
Dual Mode Tactile and Proximity Sensor
Plasma Synthesis of Nanocrystals
Nanoparticles Functionalized with Organic Molecules
Reverse Plug Cytometer for Cell Tracking
Carcinoma Immunotoxin Targeting Epidermal Growth Factor and Interleukin-4 Receptors
Cyclic Codes Error Pattern Correction Increases Hard Disk Storage Capacity
CMOS Image Sensor with Adaptive Frame Rate and High Dynamic Range
Syngas Production Using a Biomass Gasification Process
Ion Gel Gate Insulator in Field Effect Transistors
Hydraulic Energy Storage Systems
Highly Sensitive Uncooled, Narrowband, Infrared Detector
Programmable Self-assembly Method for Nanocomponents and Microcomponents
Cardiac Test Provides Three Dimensional Model of the Heart and Locates Heart Problems
Lupus Treatments Possible with Identification of High Risk Haplotype
Drug Resistant Tuberculosis Treatment
Simple Pulse-width Modulated Controller for Matrix Converters
Navigation Aid for the Visually Impaired
Thin Film Gallium Nitride has Low Dislocation Density
Uncooled, Continuously Tunable Thermal Sensor Increases Thermal Sensitivity
AMSOL 7.1: Software to Calculate Free Energies of Solvation
MovieLens Database
Biodegradable Polyester Produced From Non-toxic, Renewable Monomer
On-Demand Production of Peracetic Acid
Early Pulmonary Edema and Atrial Fibrillation Detection Using Implantable Devices
Cold Hardy Marquette Grape Variety
Aerodynamic Lenses Optimized For Nanoparticles
Error Detection Using CRC Code
Algorithm for Non-invasive Source Localization of Neural Activity
Directed Self-Assembly, Reconfigurable Manufacturing for Microsystems
Complementary Therapies and Alternative Medicine Online Learning Modules
Three Dimensional Dental Anatomy Software Program for Dentistry Students
Parity-bit Error Detection Targets Prescribed Error Events
MRI of Amyloid Plaque in the Brain
Partial Oxidation for Production of Olefins with Intact Alkane Functional Groups
Hybrid Geothermal and Fuel Cell System
Real-time Particle Detection in Semiconductor Vacuum Environment
Improved Non-coherent Ultra Wideband Radio Receiver
Pulmonary Edema Measurement Provides Alert to Worsening Heart Failure
University Compliance Program Workbook
Microbial Biosynthesis Produces Unique Flavonoids, Chalcones and Stilbenes Used in Nutraceuticals
Biodiesel and Enriched Animal Feed from Dry Distillers Grains with Solubles Created in Ethanol Production
Beginning German Language Learning Tool
High-Yield Plasma Synthesis of Luminescent Silicon Nanocrystals
SnowSweet® Apple, Cold Hardy with Sweet Tart Taste
New Voltage Controlled Oscillator Design
High Quality Digital Image Restoration Provides Faster Downloads with Less Storage and Bandwidth Requirements
Micro Fabrication Using High Resolution Xerographic Printer
3D Video from 2D Using a Single Camera System
Fabric Sleeve for Percutaneous Transluminal Device Provides Embolic Protection
Syngas from Autothermal Reforming of Ethanol
Mining Technology for Pellet Fine Removal
Mammalian Cell Culture System for Anaplasmosis Vaccine Development
PEGylated Fibrin Biomatrix for Treatment of Acute Myocardial Infarction
Low pH High-Pressure Liquid Chromatography
Mutated Opioid Receptors Block Chronic Pain Signals
Cold Hardy Frontenac gris Grape Variety
Nonlinear Post Beamforming Filter for Imaging
Reelin Protein Diagnostic Test for Mental Disorders
Ultra-thin Film Characterization Using Tunneling Ellipsometry
Bioresorbable Occlusion Device for Congenital Heart Defects
Biological Imaging Provides Full Imaging of Samples
Biological Imaging and Analyzing DNA Chips
Cellulosic Biofuel, Chemical, and Ethanol Production
Organism Design for Cellulosic Biofuel, Cellulosic Chemical, and Cellulosic Ethanol Production
Implantable Microvalve Device for Controlled Insulin Delivery in Type 1 Diabetes Patients
Targeting uPAR Overexpression on Human Glioblastoma
Ecdysteroid Biosynthetic Enzyme Inhibitors
Human Brain Anatomy Software for Interactive Neuroanatomy Study
Biological Imaging using a CMOS or CCD Image Sensor
Spray Pyrolysis Fabrication of Nanoporous Material
Direct Application of Antibiotics to Middle Ear for Ear Infection Treatment
Kappa Receptor Agonists and Delta Receptor Antagonists
Histology Software Atlas for Anatomy and Cell Biology Study
Computer-based Histology Atlas for Human Anatomy and Cell Study
Catheter for Cell Delivery in Tissue
Blue Heaven Ornamental Grass
Cold Hardy La Crescent Grape Variety
Modification of Vertical Cavity Surface Emitting Laser Emission Characteristics
Fast Iterative Decoding of Parallel Concatenated Parity Check Code
Low Complexity Signal Space Detector for DVD Channel
Highly Linear Circuits
Inhibition of Zebrafish Gene Expression
Single Wire Arc Thermal Spray for Uniform Surface Coating and Rapid Prototyping
Low Phase Noise Ring-type Voltage Controlled Oscillator
Radial Symmetry Ellipsometer
Turkey Production Improvements
Improved Nuclear Magnetic Resonance Spectroscopy Using Half-Spin Echo Data Recovery
Target for Acaricides and Cattle Tick Vaccines
Genetic Modification of Endostatin: An Anti-Angiogenic Therapeutic
Driver Assistive System - Assistance in Low Visibility Conditions
Bifidobacteria Strain Depletes Iron-Dependent Bacteria
MRI Compatible Surgical Table
Nematode Biocontrol Agent
Magnetic Separator for Taconite Processing Plant
Multimeric Immunotoxins for Cancer Treatment and Graft vs Host Disease
Rothenberger Institute
Nutrition Data System for Research – Nutritional Analysis Software
Food and Nutrient Database for Application Development and Nutrition Research
Formative Reading Assessment System for Teachers (FAST)
Biological Sample Imaging Device
More Stable and Potent Cyclic ADP-Ribose Analogs
Virtual Dental Simulation Software for Dental Assessment
Treating Neurodegenerative Diseases with Nicotine Receptor Ligands
Infusion Micropump for Drug Delivery for Treatment of Neurological Disorders and Pain Management
Medical Probe Deflection Device
Needle Placement System Provides Details for Tissue Model
Modified Sleeping Beauty Transposon Gene Transfer System
Intracranial Endoscopy System Fiber-Optic Biopsy Needle Minimizes Hemorrhaging Risk
Cell Cryopreservation for Lymphocytes Improves Hematopietic Cell Survival
Serial Graph Partitioning, Finite Element Analysis and Fill Order Reduction for Sparse Matrices
Assessing the Risk of Repeated Hospital Admission for Elderly Patients (97145)
Zestar!® Cold Hardy, Early Season Apple Variety
Vertebrates: Sleeping Beauty Transposon for Efficient DNA Delivery into Wide Array of Cells
Continuous-Text Reading Chart for Eye Examinations Measures Reading Acuity and Speed
Minnesota LIVING WITH HEART FAILURE® Questionnaire (MLHFQ)
The Minnesota LIVING WITH HEART FAILURE® Questionnaire (MLHFQ) is a validated patient-oriented measure of the adverse effects of heart failure on a patient's life.
FINPACK® Financial Software for Agricultural and Farm Management
FINPACK® is the credit analysis solution that can help lenders work smarter and serve customers better.
Honeycrisp Apples - Cold Hardy, Minnesota Apple
Explosively Crisp!
Decontamination of food and surfaces from viral contamination using photodynamic treatment
An inexpensive, non-thermal method for decontamination of foods from viral contaminants without affecting their quality.
3D printable deer head and neck model
Chronic wasting disease transmission and progression e-booklet
An informative and captivating e-booklet on chronic wasting disease transmission and progression.
A positive pressure testing booth for sample collection
Design files for a portable testing booth that facilitates safe practice of sample collection procedures on patients with infectious pathogens.
A Gown for U Project - level 1 isolation gown for emergency use
Design files for a low cost, rapidly producible, one-size-fits-all level 1 isolation gown.
Storage box to facilitate decontamination and reuse of face masks
A safe and well-ventilated storage box for N95 masks - design files and instruction videos.
MNmask Emergency-Use Face Masks
A design package for three styles of emergency-use face masks.
Minnesota Solvation (MNSOL) Database
An extensive and vetted database of free energies of solvation.
Portable aerosol hood to reduce spread of pathogens during medical procedures
A portable, transparent isolation box that facilitates safe practice of medical procedures on patients with infectious pathogens.
Coventor Emergency Ventilator - Adult Manual Resuscitator Compressor
A design package for an emergency, rapid-deployment ventilator system.
HUMBI dataset - high resolution multiview images of human body expressions
A large multiview dataset of human body expressions from a diverse population.
S100A4 inhibitor “Minnetamide” for prostate cancer treatment
Protocol for mapping sports field properties
A step-by-step, easy-to-follow protocol for collecting and analyzing surface properties of sports fields using commercially available devices and free software.
Sustainable triblock copolymers as strong, tunable, and degradable pressure sensitive adhesives
A method to produce strong, tunable, and degradable pressure sensitive adhesives from by-products of the cashew industry.
Machine learning algorithm for 3D particle field reconstruction
A machine learning algorithm for accurately reconstructing 3D particle fields.
MemPy v1.0 - Simulation software for gas separation using spiral-wound membrane modules
A simulation software tool to evaluate performance of spiral-wound membrane modules.
Peripheral Artery Disease Quality of Life (PADQOL) Questionnaire
A validated instrument to assess the physical, psychosocial and emotional effects on patients suffering from peripheral artery disease.
Living with Pulmonary Hypertension Questionnaire (LPHQ)
The Living with Pulmonary Hypertension Questionnaire (LPHQ) is a reliable and validated measure of the adverse effects of pulmonary hypertension on a patient’s life.
Position estimation and tip-over prevention system for off-road vehicles
Visualization of intracardiac electrograms on 3D heart model (VIEgram)
A software for easy visualization of intracardiac electrograms on 3D heart models.
Improving photovoltaic cell efficiency by employing highly stable, earth-abundant nanoparticle system
A novel nanomaterial for applications involving photon upconversion.
Self-supervised physics-based deep learning reconstruction without fully-sampled data
Methods for training machine learning algorithms without fully-sampled reference data for inverse problems.
Mouse models of tau variants linked to neurodegenerative disease
An improved and controlled mouse model expressing human tau P301L protein, a common mutation linked to neurodegeneration.
Hybrid charge trap transistor-MRAM memory devices (2020-102, Dr. Jian-Ping Wang)
Designs of hybrid charge trap transistor-MRAM devices for ultra-high-density non-volatile memory.
Nanoparticle bio-pesticide to improve crop health, germination, and overall yield
A material and method of application for improving crop health and yield.
Novel tensile testing apparatus for brittle materials
A device for accurately measuring tensile strength of brittle materials without requiring constitutive assumptions.
Novel process to obtain large quantities of primary cells for transplantation
A method to isolate large quantities of high quality primary cells for therapeutic transplantation through freezing and thawing organs, including organs typically considered suboptimal for donation.
Topographically conforming self-fitting garments made of active materials
A method to design and manufacture knitted garments that dynamically conforms to complex surfaces.
Nanosota-1: A series of nanobody drugs to combat COVID-19
A series of camelid nanobodies that bind to SARS-CoV-2 (COVID-19) spike protein to block infection of human cells.
Low-discrepancy Deterministic Bit-stream Processing
Two methods for fast-converging, scalable deterministic computation based-on low-discrepancy sequences.
Fully-biodegradable controlled release coatings for fertilizer
A new, fully-biodegradable material and method of preparation of slow release fertilizers.
Six-month mortality risk estimation from electronic medical record
Method for genetic engineering of legume species (2019-351, Dr. Daniel Voytas, Dr. Feng Zhang)
A method to genetically modify a variety of legume species that is efficient, fast and doesn’t require technical skills such as traditional tissue culture.
Selective bromodomain protein inhibitors that reduce cancer cell viability
Small molecules systematically designed as highly selective bromodomain inhibitors for development as cancer and inflammatory disease therapeutics.
Wound closure device
Advance Ergonomic Desk
A fully electric standing desk that is optimized for improved ergonomics, mobility, and collaboration needs of home office users.
Protocol for Golf Course Soil Moisture Mapping
A detailed, easy-to-use protocol for collecting and analyzing golf course soil moisture data using commercially available devices and free software.
Augmented sgRNAs for enhanced plant genome engineering (2019-322, Dr. Daniel Voytas)
The Voytas Lab has developed augmented sgRNAs that improve somatic cell genome editing and produce heritable modifications in plants using CRISPR/Cas9.
Dental stem cells to treat spinal cord injury
A method of treating nervous tissue damage using dental pulp stem cells that leads to neuro-regeneration with a high safety profile and low probability of patient rejection.
3D printed bionic skull for multimodal neural sensing
Elderly Mortality After Trauma (EMAT) score
A validated scoring method for predicting mortality after trauma in elderly patients at admission.
Exact-repair regenerating codes for distributed storage system
A novel framework for exact-repair regenerating codes that can optimally trade between storage and repair bandwidth in distributed storage systems.
Methods to produce high performance soft magnetic material (Minnealloy) in bulk (2019-263, Dr. Jian-Ping Wang)
Methods to prepare soft magnetic materials with high magnetization and low coercivity.
Reduce contamination from grains and powdered food
A method for scalable, non-thermal or low temperature pasteurization of powdered or particulate food.
Simplified Recycling of Multicomponent Polymer Products
Simplified, Single-Vessel Synthesis and Separation of Ammonia
An apparatus and process for simplified, high yield production of ammonia using a single vessel, isothermal reactor.
Machine learning-based sleep quality monitoring
Click-Chemistry Reagent for Mass Cytometry
A Single Device for Vaginal Dilation and Flushing
Nesocodin: A natural red colorant that’s easily synthesized
A method to synthesize a novel, natural red colorant that is biodegradable and likely non-toxic.
Fluorescence-based assay for probing lipid transfer activity
A sensitive, reproducible and quantitative assay to study lipid transfer using bicelles as model membranes.
A synergistic therapy for multi-drug resistant cancers
A synthetic polymer that targets cancer cell membranes and works synergistically with existing chemotherapeutic drugs to treat drug-resistant solid tumors.
Heart’s Desire™ Brand Redbud Spring Flowering Tree
Novel anticancer compound that targets metabolic plasticity
F-MN-D1 compound targets metabolic plasticity common to many solid tumors through inhibition of glycolysis and oxidative phosphorylation facilitating tumor growth reduction.
CoFe nanowires for remote heating using an alternating magnetic field
A nanowire material for remote, rapid and uniform heating of biological samples.
Low-end to high-end cross-technology communication via cross-decoding (XBee-XFi)
A method to enable high-throughput, concurrent cross-technology communication from low-end to high-end wireless devices using cross-decoding technique.
Minneapolis Institute of Art “Riddle Mia This” App
Patterned organic semiconductor layer for increased efficiency in OLEDs
A simple method to create a single-component diffraction grating using organic semiconductors for the improvement of outcoupling efficiency in OLEDs.
Subfield Level Model for Improved Nitrogen Fertilizer Recommendations
Biodegradable lactose-based hydrogel
A method to produce biodegradable lactose-based hydrogel from lactose-containing dairy waste.
One-Step Conversion of Methane to High Value Aromatics
3D tumor models for accurate testing of therapeutics
A method to create a 3D tumor model that accurately mimics both tumor behavior and environment for use in anti-cancer drug development.
Process to Manufacture Branched Caprolactone
Minnesota Nursing Informatics Leadership Inventory (MNILI)
Performance Driven Agglomerative Clustering Software
A TLR-2 stimulatory molecule for use as a vaccine adjuvant
A small molecule that serves as an adjuvant in vaccines through stimulation of the immune receptor, TLR-2
Delivery of developmental regulators to whole plants for the induction of genetically altered meristematic tissue (Dr. Voytas)
Research out of the Voytas Lab provides a method for the creation of genetically-altered seeds within one generation via the induction of new plant meristems.
Machine Learning-based Dynamic Activity Recommendation System
A deep learning architecture for wearable devices to evaluate, predict, and improve the quality of sleep by recommending personalized activities.
Community Detection Method for Decomposition for Optimization Problems
Unique small molecule modulators of GPCRs
Novel small molecules that bind and modulate G-protein coupled receptors (specifically Sigma 1 and 5-HT7) for therapeutic development.
Point-of-care Concussion Therapy
Antibody based treatment for Type 1 Diabetes
A humanized monoclonal antibody against Serpin B13 to treat Type 1 Diabetes.
Immunostimulatory conjugates for targeted delivery as adjuvants
Novel vaccine adjuvants composed of TLR7/TLR8 stimulating compounds conjugated to Hyaluronic Acid (HA) to achieve limited systemic exposure
iTorsion - Smartphone App for Ocular Torsion Diagnosis
An accurate, high throughput method to measure site-specific ubiquitin abundance
Isotopically balanced quantification of ubiquitination (IBAQ-Ub): A rapid, sensitive method to measure site-specific ubiquitination abundance
Cancer preventative for at risk individuals
An approach to prevent cancers through blocking the transcription factor STAT3 that leads to an 80% tumor reduction in a mouse model of disease.