SARS-CoV-2 N-protein for use in COVID-19 serological assays (2020-323)
Full length SARS-CoV-2 Nucleocapsid (N) protein expressed by bacteria for use in serological assays to detect previous COVID-19 infection in humans and animals.
SARS-CoV-2 spike receptor-binding domain for use in COVID-19 assays (2020-301)
Stably transfected mammalian cell lines that express the receptor-binding domain of the SARS-CoV-2 spike protein for use in assays and research relevant to COVID-19 and potential therapies.
Multifunctional, flexible sensor array for urethral catheters (20140233)
A new urethral catheter for simultaneous measurement of pressure distribution and neural activity.
Wearable laryngeal vibration system for Spasmodic Dysphonia (20170400)
A non-invasive neuromodulation device and method for the treatment of spasmodic dysphonia.
Pharmacological agents to prevent recurrent C. diff infection (20150362)
Cholic and bile acid derivatives that inhibit Clostridium difficile spore germination to prevent or treat C. diff infection.
Circulating tumor biomarkers for meningiomas (2020-164)
A biomarker panel for early diagnosis of meningiomas with the potential to improve patient outcomes.
Siderophore-based diagnosis of bacterial infections (20150206)
Biofeedback Hand Grip Exercise Device for Assessing Muscle Function (20170200)
A method to genetically engineer monocytes (20180236)
The first and only method available to create genetically modified CD14+ monocytes for use in research or therapy.
A streamlined method to isolate Fibroadipogenic progenitor cells from muscle (2020-195)
A method to isolate fibroadipogenic progenitor cells (FAPs) based on the presence of a single surface marker (CD73).
Monoclonal Anti-FAP for cancer research and therapeutic development (2019-131)
A plasmid encoding a recombinant monoclonal antibody against tumorigenic protein FAP in the tumor stroma that is ideal for both basic research and therapeutic drug development.
Antagomir to prevent cardiac arrhythmia (2019-069)
A novel small molecule screening platform for tauopathies (2019-123)
FRET-based biosensors that identify early toxic states of tau for use in basic research and clinical development of therapeutics for tauopathies including Alzheimer’s Disease.
MRI of Amyloid Plaque in the Brain
Nonlinear Post Beamforming Filter for Imaging
Minnesota LIVING WITH HEART FAILURE® Questionnaire (MLHFQ)
The Minnesota LIVING WITH HEART FAILURE® Questionnaire (MLHFQ) is a reliable and valid patient-oriented measure of the adverse effects of heart failure on a patient's life.
A positive pressure testing booth for sample collection
Design files for a portable testing booth that facilitates safe practice of sample collection procedures on patients with infectious pathogens.
A Gown for U Project - level 1 isolation gown for emergency use
Design files for a low cost, rapidly producible, one-size-fits-all level 1 isolation gown.
Storage box to facilitate decontamination and reuse of face masks
A safe and well-ventilated storage box for N95 masks - design files and instruction videos.
Portable aerosol hood to reduce spread of pathogens during medical procedures
A portable, transparent isolation box that facilitates safe practice of medical procedures on patients with infectious pathogens.
S100A4 inhibitor “Minnetamide” for prostate cancer treatment
Peripheral Artery Disease Quality of Life (PADQOL) Questionnaire
A validated instrument to assess the physical, psychosocial and emotional effects on patients suffering from peripheral artery disease.
Living with Pulmonary Hypertension Questionnaire (LPHQ)
The Living with Pulmonary Hypertension Questionnaire (LPHQ) is a reliable and validated measure of the adverse effects of pulmonary hypertension on a patient’s life.
Visualization of intracardiac electrograms on 3D heart model (VIEgram)
A software for easy visualization of intracardiac electrograms on 3D heart models.
Mouse models of tau variants linked to neurodegenerative disease
An improved and controlled mouse model expressing human tau P301L protein, a common mutation linked to neurodegeneration.
Novel process to obtain large quantities of primary cells for transplantation
A method to isolate large quantities of high quality primary cells for therapeutic transplantation through freezing and thawing organs, including organs typically considered suboptimal for donation.
Nanosota-1: A series of nanobody drugs to combat COVID-19
A series of camelid nanobodies that bind to SARS-CoV-2 (COVID-19) spike protein to block infection of human cells.
Selective bromodomain protein inhibitors that reduce cancer cell viability
Small molecules systematically designed as highly selective bromodomain inhibitors for development as cancer and inflammatory disease therapeutics.
Dental stem cells to treat spinal cord injury
A method of treating nervous tissue damage using dental pulp stem cells that leads to neuro-regeneration with a high safety profile and low probability of patient rejection.
Elderly Mortality After Trauma (EMAT) score
A validated scoring method for predicting mortality after trauma in elderly patients at admission.
Machine learning-based sleep quality monitoring
A Single Device for Vaginal Dilation and Flushing
Fluorescence-based assay for probing lipid transfer activity
A sensitive, reproducible and quantitative assay to study lipid transfer using bicelles as model membranes.
A synergistic therapy for multi-drug resistant cancers
A synthetic polymer that targets cancer cell membranes and works synergistically with existing chemotherapeutic drugs to treat drug-resistant solid tumors.
Novel anticancer compound that targets metabolic plasticity
F-MN-D1 compound targets metabolic plasticity common to many solid tumors through inhibition of glycolysis and oxidative phosphorylation facilitating tumor growth reduction.
3D tumor models for accurate testing of therapeutics
A method to create a 3D tumor model that accurately mimics both tumor behavior and environment for use in anti-cancer drug development.
A TLR-2 stimulatory molecule for use as a vaccine adjuvant
A small molecule that serves as an adjuvant in vaccines through stimulation of the immune receptor, TLR-2
Machine Learning-based Dynamic Activity Recommendation System
A deep learning architecture for wearable devices to evaluate, predict, and improve the quality of sleep by recommending personalized activities.
Unique small molecule modulators of GPCRs
Novel small molecules that bind and modulate G-protein coupled receptors (specifically Sigma 1 and 5-HT7) for therapeutic development.
Point-of-care Concussion Therapy
Immunostimulatory conjugates for targeted delivery as adjuvants
Novel vaccine adjuvants composed of TLR7/TLR8 stimulating compounds conjugated to Hyaluronic Acid (HA) to achieve limited systemic exposure
iTorsion - Smartphone App for Ocular Torsion Diagnosis
Cancer preventative for at risk individuals
An approach to prevent cancers through blocking the transcription factor STAT3 that leads to an 80% tumor reduction in a mouse model of disease.
Drug Delivery Device for Oral Topical Medicine
Select Optimal Therapeutic Parameters for Medical Stimulation Devices
Novel small molecules for chemotherapy sensitization
Novel phenoxyphenyldeazaflavin compounds that sensitize cancer cells to widely used topoisomerase 2 poisons.
Quality Control Test for Pathogenic Bacteria Contaminated Water
New Prodrugs for Preventing and Treating Alzheimer's Disease
Assay to measure intrinsic efficiency of GPCR ligands
FRET-based GPCR biosensors to measure specific ligand activation in a cell independent manner.
Patient Controlled Dynamic Therapeutic Compression Tension Garment
MHC Class II Molecules with Enhanced Co-receptor Affinity
A novel chemotherapy drug with reduced patient side-effects
A novel anti-cancer compound that inhibits translation and induces p53 in a DNA-damage independent manner to cause cell cycle arrest and apoptosis.
Non-invasive Neuromodulation for Reversible Modulation of Neural Activity
A method for targeted modulation of neural activity using transcranial low intensity focused ultrasound.
MyStrengths MyHealth™
Microinjection for Single Cell Gene Manipulation
Segmenting 3D Bone Computed Tomography Data
Tosedostat (CHR-2797) as a Potential Analgesic
Engineering Human CD64 Chimeric Receptors for Immune Therapy
Integrated Traumatic Brain Injury Catheter (iTBI)
Real-Time Reporter and Efficient Enzymes for DNA Editing
Optimized Radio Frequency Pulses Generated From Magnetic Resonance User Defined Parameters
Scan-Specific Machine Learning Reconstruction for MRI
Augmented non-invasive hearing system
3D Printed Stretchable Tactile Sensors with Electronic Ink
Specific kinase biosensors to probe cancer metabolism
Substrate peptides for Ser/Thr kinases to investigate the metabolic processes of cancer cells.
Sliding Windowed Infinite Fourier Transform (SWIFT)
MRI and Spectroscopy Multi-part Body Coil
3D Microscale Isotropic Metamaterials
Biased Unmatched Bivalent LigandsTargeting Asymmetrically Signaling GPCR Homodimers
One-Year Mortality Risk Estimates from Electronic Medical Record Data
Probes for Biosynthesis of Bacterial Cell Wall
Unique compounds to treat obesity
Unique compounds are the first-ever to target melanocortin receptor 3 in an effort to treat obesity without increasing blood pressure.
Increase Signal-to-noise Ratio in Imaging Data
Bacterial Histidine Kinase Inhibitor
Faster MRI Acquistion with Motion Robustness
Tau-targeting Peptides Treat Neurodegenerative Diseases
Tunable Neural Electrodes for MRI-Compatible Brain Signal Recordings
A discrete and effective wearable breast pump for nursing mothers
A quiet and concealed wearable breast pump that mimics infant suckling using mechanical compression and heat; increasing milk expression as well as convenience and comfort.
Myocardial Viability Functional Assessment
Dynamic Quantification of Myocardial Tissue MRI
Skin Care Formulations for Preventing and Treating Skin Cancer
Orthopedic Meniscus Repair Implant, Introducer and Delivery System
Remedy for Heart Failure with Preserved Ejection Fraction
Conformable Dual-mode Ultrasound Transducers for Neuromodulation
Rationale Design of Inhibitors based on Crystal Structures of ssDNA Bound to APOBEC
Single Voxel MR Spectroscopy of Human Brain with Automatic Voxel Positioning
Solar UV-Induced Skin Cancer Inhibitor
Magnetization Transfer Contrast Preparation
Particle Swarm Optimization for Programming Neuromodulation Systems
Multi-modal Neuromodulation Therapy Promotes Sleep
Scaffolds for Cancer Cell Ablation
Pediatric Tracheo-bronchomalacia Stent and Deployment System
Fluorescence-based Detection of Kinase Allostery for High-throughput Allosteric Inhibitor Discovery
Mimicked Calcified Annulus Model for Preclinical Assessment of TAVR Devices
Motion-Robust Cardiac B1+ Mapping of the Transmit Field
Imaging Source Distribution from Electromagnetic Signals
High-voltage, Fully-integrated, High-density Microstimulator with Charge Balancing
Simultaneous RF Signal Transmission and Reception in MRI (20160420)
Neural Recording under Electrical Microstimulation
Adaptive Immune Response Stimulated with TLR8 and Dual TLR7/TLR8 Agonists
Compliant Aortic Stent Graft
Black-Blood T1 Myocardial Mapping to Remove Partial Voluming Effects
Kinase assay to aid in development of therapeutics for acute myeloid leukemia
Peptide substrates to sensitively and specifically measure the real-time activity of FLT3, a kinase linked to acute myeloid leukemia.
PDAC Treatment with High Antiproliferative Activity Against MiaPaca-2
Lung Biopsy Tool
Treating Tumors with High Intensity Focused Ultrasound
Novel inhibitors of HINT1 to treat neuropathic pain and addiction
Small-molecule inhibitors of hHint1 (and their synthesis) for use in basic CNS research and treatment of neuropathic pain and addiction.
3D Shoulder Motion Measurement System
Optimizing Gene Editing in NK Cells for Therapy and Research
Ultrasound-based Hearing Aid
Biosynthetic Route to Serofendic Acid
Anti-obesity and Weight Control Drugs Target Melanocortin Receptor
Smart Clothing with Dynamically Controlled Compression
Improved Lumbar Puncture And Epidural Accuracy
Designing 2D and 3D Adiabatic Pulses
Neuromodulator for Simultaneous Stimulation and Signal Reception
Improved Craniotome to Prevent Dural Tear
Efficient release of affinity-captured cells
A method to effectively release affinity-captured cells.
Developing Highly Specific Monoclonal Antibodies to Peptide in the Context of MHC II
Nonsurgical Method for Restoring Tooth Enamel
Radiofrequency Antenna Array with Electric Dipole and Loop Elements
Biomarker for Diagnosis of Aggressive Breast Cancer
Warming of Cryopreserved Biomaterials using Laser Assisted Gold Nanorods
Catheter Based Targeted Extracorporeal Membrane Oxygenator (ECMO)
Improved Pertussis Vaccine
Algorithm for Discovering Genetic Interactions in Genome-Wide Association Studies (BridGE)
Multimodal Synchronization, Sound & Electrical Stimulation, Hearing Aid (mSync-hEAR)
Hydrophobic Surfaces for Tooth Tissues
Adaptive Refocusing of Ultrasound Arrays Using Synthetic Aperture Imaging Data
Graphene Formaldehyde Sensor (20150354, Dr. Tianhong Cui)
Pre-surgical Pulmonary Nodule Localization Coil (20150351, Dr. Michael Rosenberg)
Nucleic Acid Delivery to the Liver for Hemophilia and Lysosomal Storage Disease Treatment (20150339, Dr. Reineke)
Kinase biosensor for individualized cancer therapy (20150289, Dr. Laurie Parker)
A method to sensitively and specifically detect the activity of multiple kinases, from multiple samples in a traceable manner.
Dental Mercury Capture Device (20150218, Dr. Sandra Myers)
Lower Extremity Edema Monitor (20150192, Dr. Rajesh Rajamani)
Deep Brain Stimulation Using Magnetic Brain Array (20150177, Dr. Jian-Ping Wang)
Improved Deep Brain Stimulation Target Selectivity (20150170, Dr. Shalom Michaeli)
Soft Catheter Surgical Robot for Heart Disease (20150147, Dr. Tim Kowalewski)
Increased efficiency of CRISPR-Cas9 genome editing (20150143, Dr. Wendy Gordon)
An approach that increases the efficiency of CRISPR/Cas-9 genome editing 30-fold by fusing Cas9 to an HUH endonuclease tethered to the desired donor DNA.
Improved MRI Quality with Gradient Modulation Pulse Sequence (20150133, Dr. Kobayashi, Dr. Garwood)
Acousto-electromagnetic Imaging of the Brain (20150126, Dr. Bin He)
Time Efficient Arterial Spin Labeling Imaging with Segmented Multiband-acquisition (20150097, Dr. Greg Metzger)
Improved MRI Method Uses Temperature Rise Contraints (20150061, Dr. Moortele)
Therapeutic compound for chronic inflammatory pain without dependence or tolerance (20140357, Dr. Philip Portoghese)
An analgesic compound without side effects that relieves chronic pain associated with arthritis, sickle cell disease, chemotherapy, AIDs and inflammation.
Mapping Prostate Cancer from Multi-parametric MRI with Improved Predictive Models (20140287, Dr. Greg Metzger)
Multi-purpose Arm Ergometer Design (20140266, Dr. Gary Goldish)
In-vivo MRI Radiofrequency Pulses Robust against Respiration Induced Errors (20140236, Dr. Kamil Ugurbil)
Multi-band SWIFT Improves MRI (20140121, Dr. Idiyatullin, Dr. Garwood)
Generalized Multiband Slice Accelerated Imaging (20140093, Dr. Dingxin Wang)
Reduced-power SWIFT Magnetic Resonance Imaging (20140052, Dr. Jinjin Zhang, Dr. Garwood)
Magnetic Resonance Electrical Properties Tomography (20130259, Dr. Bin He)
Multislice Multiband Excitation with Parallel Transmission for B1 Homogenization and Power Reduction (20130170)
IV Line Lifting Device (20130136, Dr. Mary Hooke)
Intraoral Dental MRI Coil (20130110, Dr. Michael Garwood)
MRI Signal Separation using Iterative Calibration (20130079, Dr. Kamil Ugurbil)
Enhancing Cardiac Function Using Short Protein Inhibiting DNAs and RNAs (20120271, Dr. Michael Bowser)
MRI Coil Amplifiers (20120122, Dr. Tommy Vaughan)
Human Whole-Body Imaging at 7T (20120120, Dr. Tommy Vaughan)
Electrical Auto-tuning for Ultra-High-Field MRI RF Coils (20120119, Dr. Tommy Vaughan)
MRI Method Reduces Peak Power for Multiband Images (20120077, Dr. Kamil Ugurbil)
Synchronized Multi-Modal Tinnitus Therapy (20120070, Dr. Hubert Lim)
A non-invasive or minimally-invasive method for the suppression of tinnitus using synchronized brain stimulation.
Beam Steering Resonance along a Spatiotemporal Trajectory for MRI (20120060, Dr. Michael Garwood)
MRI Pulse Sequence: Steering Resonance over the Object (20120049, Dr. Michael Garwood)
Faster Functional and Diffusion MRI of the Brain (20110139, Dr. Kamil Ugurbil)
Lower Specific Absorption Rate for Multiband MRI (20110093, Dr. Kamil Ugurbil)
Faster Whole Brain Imaging (20110092, Dr. Kamil Ugurbil)
Generation of NK and Innate Lymphoid Cells from human stem cells (20110085, Dr. Michael Verneris)
Drs. Verneris, Miller and Blazar developed a method to create large numbers of Natural Killer cells and Innate Lymphoid Cells from hematopoietic stem cells.
Insulin Producing Cells from Pluripotent Stem Cells (20100245)
Ultrasound System for Characterization and Image-guided Therapy of Blood Vessel Diseases (20100155)
Digital Pathology Quantitative Immunohistochemistry Software
Digital Pathology Quantitative Immunohistochemistry Software