Zika as an oncolytic virus to treat brain tumors
A method to treat aggressive brain cancers using Zika as an oncolytic virus combined with anti-cancer vaccinations.
Therapeutic target for treatment of ataxia
A newly identified pathway that represents a therapeutic target for the prevention and treatment of ataxia.
Use of extracellular vesicles to enhance colorectal cancer therapeutics
Cancer-derived extracellular vesicles (EVs) that enhance the efficacy of checkpoint inhibitor therapeutics for colorectal tumors.
Generating teratoma-derived skeletal muscle stem cells
A method for generating teratoma-derived skeletal muscle stem cells with functional regenerative capacity.
Small molecules with antiproliferative activity against pancreatic cancer cells
Small molecules that show antiproliferative activity against the pancreatic cancer cell line MiaPaca-2.
AgRP-Derived melanocortin-5 receptor peptide antagonists
AgRP derived scaffolds composed of natural (Tyr, Ala, Val, Asn) and unnatural amino acids (Dap) with antagonist activity at the mouse MC5R
Treating trauma-induced acute blood loss
Novel formulations of D-β-hydroxybutyrate and melatonin improve survival from hemorrhagic shock.
Pain therapy without the risk of respiratory depression, addiction or abuse
An analgesic combination of peripherally restricted opioids that eliminates the risk of respiratory depression, chemical addiction or abuse.
3D printable bovine head model
AGRP-derived melanocortin receptor ligands
Identifying a selective MC4R antagonist for appetite modulation
Chimeric melanocortin receptor ligands
Melanocortin-4 receptor ligand reduces food intake in mice
Selective melanocortin receptor ligands
Potential dual-ligand approach to weight management
Risk-free in situ non animal (RISNA) surrogate assay for African swine fever virus
A method of using a surrogate virus to confirm inactivation of African Swine Fever Virus(ASFV)
A novel approach for bioprinting complex tissue models
A new method to align cells in muscle tissue using long, pre-aligned microtissues, which are suspended in a bio-ink and printed using a 3D extrusion bioprinter to form larger macrotissues.
Minimally invasive diagnostic for osteosarcoma in dogs
A panel of six definitive biomarkers that can be isolated from a canine blood sample for the detection of minimal residual disease and monitoring remission in dogs treated for osteosarcoma.
A method to identify cell-free biomarkers of cancers and other diseases
A cost-effective method to discover biomarkers for a variety of cancers that can be measured in a blood sample and can inform risk, diagnosis, prognosis and predict responses to therapy.
Assessing tumor behavior and response to therapy
A method to identify biomarkers for the detection of tumor behavior and/or increased risk for tumor metastasis in order to improve patient outcomes in both humans and animals.
Machine learning for early cancer detection
A machine learning method to train and validate algorithms to classify cancer risk based on a blood sample.
Fast and reliable neutralization antibodies assay for AAV gene therapy (2020-121)
An assay to measure neutralization antibodies for adeno-associated viral vectors in gene therapy, to screen patients for clinical trials and treatment.
Continuous honey bee cell-line, AmE-711 (2020-240)
The first and only honey bee cell-line available for use in research and experimental testing.
Siderophore-based diagnosis of bacterial infections (20150206)
Monoclonal Anti-FAP for cancer research and therapeutic development (2019-131)
A plasmid encoding a recombinant monoclonal antibody against tumorigenic protein FAP in the tumor stroma that is ideal for both basic research and therapeutic drug development.
MRI of Amyloid Plaque in the Brain
Mammalian Cell Culture System for Anaplasmosis Vaccine Development
Mutated Opioid Receptors Block Chronic Pain Signals
3D printed deer head and neck model
Chronic wasting disease transmission and progression e-booklet
An informative and captivating e-booklet on chronic wasting disease transmission and progression.
Selective bromodomain protein inhibitors that reduce cancer cell viability
Small molecules systematically designed as highly selective bromodomain inhibitors for development as cancer and inflammatory disease therapeutics.
A synergistic therapy for multi-drug resistant cancers
A synthetic polymer that targets cancer cell membranes and works synergistically with existing chemotherapeutic drugs to treat drug-resistant solid tumors.
CoFe nanowires for remote heating using an alternating magnetic field
A nanowire material for remote, rapid and uniform heating of biological samples.
A TLR-2 stimulatory molecule for use as a vaccine adjuvant
A small molecule that serves as an adjuvant in vaccines through stimulation of the immune receptor, TLR-2
Antibody based treatment for Type 1 Diabetes
A humanized monoclonal antibody against Serpin B13 to treat Type 1 Diabetes.
Immunostimulatory conjugates for targeted delivery as adjuvants
Novel vaccine adjuvants composed of TLR7/TLR8 stimulating compounds conjugated to Hyaluronic Acid (HA) to achieve limited systemic exposure
Novel small molecules for chemotherapy sensitization
Novel phenoxyphenyldeazaflavin compounds that sensitize cancer cells to widely used topoisomerase 2 poisons.
Patient Controlled Dynamic Therapeutic Compression Tension Garment
MHC Class II Molecules with Enhanced Co-receptor Affinity
A novel dual-action drug targeting cancer and respiratory syndromes
A novel compound inhibiting translation and inducing p53 independently of DNA damage, with potential for treating both cancer and acute respiratory syndromes.
Microinjection for Single Cell Gene Manipulation
Referenceless Nyquist Ghost Correction for Echo Planar Imaging (EPI)
Segmenting 3D Bone Computed Tomography Data
Tosedostat (CHR-2797) as a Potential Analgesic
Real-Time Reporter and Efficient Enzymes for DNA Editing
Optimized Radio Frequency Pulses Generated From Magnetic Resonance User Defined Parameters
Scan-Specific Machine Learning Reconstruction for MRI
Sliding Windowed Infinite Fourier Transform (SWIFT)
3D Microscale Isotropic Metamaterials
Probes for Biosynthesis of Bacterial Cell Wall
Unique compounds to treat obesity
Unique compounds are the first-ever to target melanocortin receptor 3 in an effort to treat obesity without increasing blood pressure.
Denoising Magnetic Resonance Imaging Data
NOise reduction with DIstribution Corrected (NORDIC) technique for improving MRI imaging.
Bacterial Histidine Kinase Inhibitor
Faster MRI Acquistion with Motion Robustness
Tunable Neural Electrodes for MRI-Compatible Brain Signal Recordings
Myocardial Viability Functional Assessment
Dynamic Quantification of Myocardial Tissue MRI
Orthopedic Meniscus Repair Implant, Introducer and Delivery System
Conformable Dual-mode Ultrasound Transducers for Neuromodulation
Rationale Design of Inhibitors based on Crystal Structures of ssDNA Bound to APOBEC
Single Voxel MR Spectroscopy of Human Brain with Automatic Voxel Positioning
Solar UV-Induced Skin Cancer Inhibitor
Magnetization Transfer Contrast Preparation
Multi-modal Neuromodulation Therapy Promotes Sleep
Pediatric Tracheo-bronchomalacia Stent and Deployment System
Mimicked Calcified Annulus Model for Preclinical Assessment of TAVR Devices
Motion-Robust Cardiac B1+ Mapping of the Transmit Field
Imaging Source Distribution from Electromagnetic Signals
Adaptive Immune Response Stimulated with TLR8 and Dual TLR7/TLR8 Agonists
Black-Blood T1 Myocardial Mapping to Remove Partial Voluming Effects
PDAC Treatment with High Antiproliferative Activity Against MiaPaca-2
Lung Biopsy Tool
Novel inhibitors of HINT1 to treat neuropathic pain and addiction
Small-molecule inhibitors of hHint1 (and their synthesis) for use in basic CNS research and treatment of neuropathic pain and addiction.
Porcine B lymphoma cell lines
Three porcine B cell lines (Murtaugh001, Murtaugh002, Murtaugh003) established by 3 rounds of limiting dilution from splenic and subiliac lymph node lymphomas.
Smart Clothing with Dynamically Controlled Compression
Neuromodulator for Simultaneous Stimulation and Signal Reception
Improved Craniotome to Prevent Dural Tear
Efficient release of affinity-captured cells
A method to effectively release affinity-captured cells.
Developing Highly Specific Monoclonal Antibodies to Peptide in the Context of MHC II
Nonsurgical Method for Restoring Tooth Enamel
Peptide Activation of T Cells for Cancer Immunotherapy
Radiofrequency Antenna Array with Electric Dipole and Loop Elements
Warming of Cryopreserved Biomaterials using Laser Assisted Gold Nanorods
A method for rapid, uniform warming of cryopreserved biomaterials using laser-assisted gold nanorods.
Improved Pertussis Vaccine
Algorithm for Discovering Genetic Interactions in Genome-Wide Association Studies (BridGE)
Hydrophobic Surfaces for Tooth Tissues
Adaptive Refocusing of Ultrasound Arrays Using Synthetic Aperture Imaging Data
Live Attenuated Viral Vaccines
Catheter System with Guidewire Compartmentalization (20150223, Dr. Rumi Faizer)
HerdIn:Form(er): Mobile Questionnaire for Livestock Epidemiology Research (20150194, Dr. Andres Perez)
Lower Extremity Edema Monitor (20150192, Dr. Rajesh Rajamani)
Deep Brain Stimulation Using Magnetic Brain Array (20150177, Dr. Jian-Ping Wang)
Improved Deep Brain Stimulation Target Selectivity (20150170, Dr. Shalom Michaeli)
Increased efficiency of CRISPR-Cas9 genome editing (Dr. Wendy Gordon)
An approach that increases the efficiency of CRISPR/Cas-9 genome editing 30-fold by fusing Cas9 to an HUH endonuclease tethered to the desired donor DNA.
Improved MRI Quality with Gradient Modulation Pulse Sequence (20150133, Dr. Kobayashi, Dr. Garwood)
Time Efficient Arterial Spin Labeling Imaging with Segmented Multiband-acquisition (20150097, Dr. Greg Metzger)
Improved MRI Method Uses Temperature Rise Contraints (20150061, Dr. Moortele)
Therapeutic compound for chronic inflammatory pain without dependence or tolerance (20140357, Dr. Philip Portoghese)
An analgesic compound without side effects that relieves chronic pain associated with arthritis, sickle cell disease, chemotherapy, AIDs and inflammation.
Mapping Prostate Cancer from Multi-parametric MRI with Improved Predictive Models (20140287, Dr. Greg Metzger)
In-vivo MRI Radiofrequency Pulses Robust against Respiration Induced Errors (20140236, Dr. Kamil Ugurbil)
Microbiome Profiling Technique for Improving Commercial Turkey Production (20140230, Dr. Timothy Johnson)
Multi-band SWIFT Improves MRI (20140121, Dr. Idiyatullin, Dr. Garwood)
Generalized Multiband Slice Accelerated Imaging (20140093, Dr. Dingxin Wang)
Bovine Tuberculosis Screening (20140058, Dr. Srinand Sreevatsan)
Reduced-power SWIFT Magnetic Resonance Imaging (20140052, Dr. Jinjin Zhang, Dr. Garwood)
Hay Prices per Ton Calculator App (20130300, Dr. Krishona Martinson)
Healthy Horse App Calculates Weight (20130294, Dr. Krishona Martinson)
Multislice Multiband Excitation with Parallel Transmission for B1 Homogenization and Power Reduction (20130170)
Intraoral Dental MRI Coil (20130110, Dr. Michael Garwood)
MRI Signal Separation using Iterative Calibration (20130079, Dr. Kamil Ugurbil)
Enhancing Cardiac Function Using Short Protein Inhibiting DNAs and RNAs (20120271, Dr. Michael Bowser)
MRI Method Reduces Peak Power for Multiband Images (20120077, Dr. Kamil Ugurbil)
Synchronized Multi-Modal Tinnitus Therapy (20120070, Dr. Hubert Lim)
A non-invasive or minimally-invasive method for the suppression of tinnitus using synchronized brain stimulation.
Canine Lymphoma Prognostic Classification (20120065, Dr. Jaime Modiano)
MRI Pulse Sequence: Steering Resonance over the Object (20120049, Dr. Michael Garwood)
Faster Functional and Diffusion MRI of the Brain (20110139, Dr. Kamil Ugurbil)
Lower Specific Absorption Rate for Multiband MRI (20110093, Dr. Kamil Ugurbil)
Faster Whole Brain Imaging (20110092, Dr. Kamil Ugurbil)
Generation of NK and Innate Lymphoid Cells from human stem cells (20110085, Dr. Michael Verneris)
Drs. Verneris, Miller and Blazar developed a method to create large numbers of Natural Killer cells and Innate Lymphoid Cells from hematopoietic stem cells.