Ovarian cancer prognostic test for predicting response to chemotherapy and bevacizumab
A prognostic molecular test for predicting ovarian cancer patient response to platinum-based chemotherapy and/or treatment with bevacizumab.
Early detection of ovarian cancer using a multiprotein classifier
A blood test for detecting ovarian cancer with over 90% accuracy by monitoring key protein levels.
Surface markers for identification and isolation of skeletal muscle stem cells
A list of cell surface marker antibodies that can identify and isolate (or purify) human skeletal muscle stem cells.
HUH fusion enzymes for multiplex protein labeling
HUH fusion tags are novel, robust endonucleases that allow proteins and DNA to be linked covalently in one simple step
Nanominne-1: novel virus-like particle (nanoparticle) vaccines to prevent SARS-CoV-2 infections
Series of novel vaccines containing 60 copies of SARS-CoV-2 antigens displayed in ordered array on a virus-like particle scaffold (nanoparticle)
Targeted Artificial DNA Replisome (TADR) a Tool for Targeted Mutagenesis
TADR is a protein-complex designed to target and mutate specific genes on plasmid in vivo
Engineered SARS-CoV-2 spike ectodomain for COVID-19 diagnostic assays
Engineered SARS-CoV-2 spike ectodomain expressed from stably transfected mammalian cell lines to be used as an effective diagnostic antigen against different SARS-CoV-2 variants
Risk-free in situ non animal (RISNA) surrogate assay for African swine fever virus
A method of using a surrogate virus to confirm inactivation of African Swine Fever Virus(ASFV)
Minimally invasive diagnostic for osteosarcoma in dogs
A panel of six definitive biomarkers that can be isolated from a canine blood sample for the detection of minimal residual disease and monitoring remission in dogs treated for osteosarcoma.
A method to identify cell-free biomarkers of cancers and other diseases
A cost-effective method to discover biomarkers for a variety of cancers that can be measured in a blood sample and can inform risk, diagnosis, prognosis and predict responses to therapy.
Assessing tumor behavior and response to therapy
A method to identify biomarkers for the detection of tumor behavior and/or increased risk for tumor metastasis in order to improve patient outcomes in both humans and animals.
Machine learning for early cancer detection
A machine learning method to train and validate algorithms to classify cancer risk based on a blood sample.
Circulating tumor biomarkers for meningiomas (2020-164)
A biomarker panel for early diagnosis of meningiomas with the potential to improve patient outcomes.
A streamlined method to isolate Fibroadipogenic progenitor cells from muscle (2020-195)
A method to isolate fibroadipogenic progenitor cells (FAPs) based on the presence of a single surface marker (CD73).
Monoclonal Anti-FAP for cancer research and therapeutic development (2019-131)
A plasmid encoding a recombinant monoclonal antibody against tumorigenic protein FAP in the tumor stroma that is ideal for both basic research and therapeutic drug development.
A novel small molecule screening platform for tauopathies (2019-123)
FRET-based biosensors that identify early toxic states of tau for use in basic research and clinical development of therapeutics for tauopathies including Alzheimer’s Disease.
CoFe nanowires for remote heating using an alternating magnetic field
A nanowire material for remote, rapid and uniform heating of biological samples.
An accurate, high throughput method to measure site-specific ubiquitin abundance
Isotopically balanced quantification of ubiquitination (IBAQ-Ub): A rapid, sensitive method to measure site-specific ubiquitination abundance
Particle Swarm Optimization for Programming Neuromodulation Systems
Black-Blood T1 Myocardial Mapping to Remove Partial Voluming Effects
Kinase assay to aid in development of therapeutics for acute myeloid leukemia
Peptide substrates to sensitively and specifically measure the real-time activity of FLT3, a kinase linked to acute myeloid leukemia.
Efficient release of affinity-captured cells
A method to effectively release affinity-captured cells.
Developing Highly Specific Monoclonal Antibodies to Peptide in the Context of MHC II
Endometrial Cancer Recurrence Risk Biomarker
Algorithm for Discovering Genetic Interactions in Genome-Wide Association Studies (BridGE)
Gut Microbiome Analysis for Detecting Colon Cancer Mutations
Circulating Tumor Cell Detection with New Reagents (20140299, Dr. Jayanth Panyam)
Bovine Tuberculosis Screening (20140058, Dr. Srinand Sreevatsan)
Magnetic Resonance Electrical Properties Tomography (20130259, Dr. Bin He)
Reagent for Dual Protein Labeling (20130255, Dr. Mark Distefano)
Matrix for Storage of Biofluid Specimens and Biological Drugs at Room Temperature (20130180, Dr. Alpetkin Aksan)
This technology is a novel biopreservation sponge for storage of biofluid specimens and biological drugs at room temperature that prevents degradation and aggregation of biomolecules.