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Treating epilepsy via targeted therapy to the endopiriform nucleus (EPN)

A system and method for treating epilepsy and other neurological disorders by deep brain stimulation targeted to the EPN using ultrahigh field MRI.

Novel compounds for treatment of neurodegenerative disease and chronic pain

Novel alpha2-adrenergic agonists with neuroprotective and/or analgesic properties.

Steerable magneto-photonic particles for targeted delivery and collection of light

An embeddable magneto-photonic microparticle that can be externally positioned and orientated for targeted delivery and collection of light.

Chaotic desynchronization of neural populations with non-pulsatile inputs

A method to identify stimulation parameters for desynchronizing a set of neurons.

Use of sulfanegen and its analogs for prevention and treatment for neurodegenerative disorders

A 3-mercaptopyruvate prodrug, sulfanegen, that reduces neuroinflammation and oxidative stress for therapeutic use in neurodegenerative diseases.

Circulating tumor biomarkers for meningiomas (2020-164)

A biomarker panel for early diagnosis of meningiomas with the potential to improve patient outcomes.

A novel small molecule screening platform for tauopathies (2019-123)

FRET-based biosensors that identify early toxic states of tau for use in basic research and clinical development of therapeutics for tauopathies including Alzheimer’s Disease.

Machine learning algorithm for 3D particle field reconstruction

A machine learning algorithm for accurately reconstructing 3D particle fields.

Non-invasive Neuromodulation for Reversible Modulation of Neural Activity

A method for targeted modulation of neural activity using transcranial low intensity focused ultrasound.

Directional Coordinated Reset Deep Brain Stimulation (DBS) (20180061)

Scan-Specific Machine Learning Reconstruction for MRI

Augmented non-invasive hearing system

Sliding Windowed Infinite Fourier Transform (SWIFT)

Tunable Neural Electrodes for MRI-Compatible Brain Signal Recordings

Large 3D Printed Skull Window for Neuroscience Research

Conformable Dual-mode Ultrasound Transducers for Neuromodulation

Magnetization Transfer Contrast Preparation

Particle Swarm Optimization for Programming Neuromodulation Systems

Multi-modal Neuromodulation Therapy Promotes Sleep

Novel inhibitors of HINT1 to treat neuropathic pain and addiction

Small-molecule inhibitors of hHint1 (and their synthesis) for use in basic CNS research and treatment of neuropathic pain and addiction.

Neuromodulator for Simultaneous Stimulation and Signal Reception

Multimodal Synchronization, Sound & Electrical Stimulation, Hearing Aid (mSync-hEAR)

Deep Brain Stimulation Using Magnetic Brain Array (20150177, Dr. Jian-Ping Wang)

Improved Deep Brain Stimulation Target Selectivity (20150170, Dr. Shalom Michaeli)

Deep Brain Stimulation Settings Optimization Algorithm (20150160, Dr. Matthew Johnson)

Therapeutic compound for chronic inflammatory pain without dependence or tolerance (20140357, Dr. Philip Portoghese)

An analgesic compound without side effects that relieves chronic pain associated with arthritis, sickle cell disease, chemotherapy, AIDs and inflammation.

Magnetic Resonance Electrical Properties Tomography (20130259, Dr. Bin He)

Multislice Multiband Excitation with Parallel Transmission for B1 Homogenization and Power Reduction (20130170)

Synchronized Multi-Modal Tinnitus Therapy (20120070, Dr. Hubert Lim)

A non-invasive or minimally-invasive method for the suppression of tinnitus using synchronized brain stimulation.