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Pharmacological agents to prevent recurrent C. diff infection (20150362)

Cholic and bile acid derivatives that inhibit Clostridium difficile spore germination to prevent or treat C. diff infection.

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Siderophore-based diagnosis of bacterial infections (20150206)

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Monoclonal Anti-FAP for cancer research and therapeutic development (2019-131)

A plasmid encoding a recombinant monoclonal antibody against tumorigenic protein FAP in the tumor stroma that is ideal for both basic research and therapeutic drug development.

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Food Supply Chain Risk Assessment and Mitigation Tools (20180173)

Technology #20180173-20180174-20180175-20180176-20180177-20180178

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E. Coli Fermentation of Glycerol from Biodiesel Waste into Ethanol

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Geothermal Power Generation from Carbon Dioxide Sequestration Uses Renewable Resources

Geothermal Power Generation: Clean Energy from Carbon Dioxide Sequestration

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Corn Stover Agglomerates for Oil Absorption

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High Yield Ammonia Production

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Ammonia Production without Molecular Hydrogen for use in Fertilizer Production

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Bactericidal Lanbiotic Inhibits Gram-negative Bacteria

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Cold Hardy Marquette Grape Variety

From $200.00
2 licensing options
MRI of Amyloid Plaque in the Brain

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0 licensing option
Biodiesel and Enriched Animal Feed from Dry Distillers Grains with Solubles Created in Ethanol Production

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0 licensing option
SnowSweet® Apple, Cold Hardy with Sweet Tart Taste

From $1.25
2 licensing options
Mammalian Cell Culture System for Anaplasmosis Vaccine Development

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Mutated Opioid Receptors Block Chronic Pain Signals

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Cold Hardy Frontenac gris Grape Variety

From $200.00
2 licensing options
Nonlinear Post Beamforming Filter for Imaging

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0 licensing option
Ecdysteroid Biosynthetic Enzyme Inhibitors

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0 licensing option
Blue Heaven Ornamental Grass

From $1000.00
1 licensing option
Cold Hardy La Crescent Grape Variety

From $200.00
2 licensing options
Turkey Production Improvements

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0 licensing option
Bifidobacteria Strain Depletes Iron-Dependent Bacteria

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Nematode Biocontrol Agent

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Nutrition Data System for Research – Nutritional Analysis Software

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Food and Nutrient Database for Application Development and Nutrition Research

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Zestar!® Cold Hardy, Early Season Apple Variety

From $1.25
2 licensing options
FINPACK® Financial Software for Agricultural and Farm Management

FINPACK® is the credit analysis solution that can help lenders work smarter and serve customers better.

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0 licensing option
Honeycrisp Apples - Cold Hardy, Minnesota Apple

Explosively Crisp!

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Decontamination of food and surfaces from viral contamination using photodynamic treatment

An inexpensive, non-thermal method for decontamination of foods from viral contaminants without affecting their quality.

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3D printable deer head and neck model

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Chronic wasting disease transmission and progression e-booklet

An informative and captivating e-booklet on chronic wasting disease transmission and progression.

FREE OF CHARGE
2 licensing options
S100A4 inhibitor “Minnetamide” for prostate cancer treatment

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Sustainable triblock copolymers as strong, tunable, and degradable pressure sensitive adhesives

A method to produce strong, tunable, and degradable pressure sensitive adhesives from by-products of the cashew industry.

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Nanoparticle bio-pesticide to improve crop health, germination, and overall yield

A material and method of application for improving crop health and yield.

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Novel process to obtain large quantities of primary cells for transplantation

A method to isolate large quantities of high quality primary cells for therapeutic transplantation through freezing and thawing organs, including organs typically considered suboptimal for donation.

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Fully-biodegradable controlled release coatings for fertilizer

A new, fully-biodegradable material and method of preparation of slow release fertilizers.

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Method for genetic engineering of legume species (2019-351, Dr. Daniel Voytas, Dr. Feng Zhang)

A method to genetically modify a variety of legume species that is efficient, fast and doesn’t require technical skills such as traditional tissue culture.

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Selective bromodomain protein inhibitors that reduce cancer cell viability

Small molecules systematically designed as highly selective bromodomain inhibitors for development as cancer and inflammatory disease therapeutics.

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Augmented sgRNAs for enhanced plant genome engineering (2019-322, Dr. Daniel Voytas)

The Voytas Lab has developed augmented sgRNAs that improve somatic cell genome editing and produce heritable modifications in plants using CRISPR/Cas9.

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3D printed bionic skull for multimodal neural sensing

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Reduce contamination from grains and powdered food

A method for scalable, non-thermal or low temperature pasteurization of powdered or particulate food.

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Simplified, Single-Vessel Synthesis and Separation of Ammonia

An apparatus and process for simplified, high yield production of ammonia using a single vessel, isothermal reactor.

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Nesocodin: A natural red colorant that’s easily synthesized

A method to synthesize a novel, natural red colorant that is biodegradable and likely non-toxic.

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Fluorescence-based assay for probing lipid transfer activity

A sensitive, reproducible and quantitative assay to study lipid transfer using bicelles as model membranes.

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A synergistic therapy for multi-drug resistant cancers

A synthetic polymer that targets cancer cell membranes and works synergistically with existing chemotherapeutic drugs to treat drug-resistant solid tumors.

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Heart’s Desire™ Redbud Spring Flowering Tree

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Novel anticancer compound that targets metabolic plasticity

F-MN-D1 compound targets metabolic plasticity common to many solid tumors through inhibition of glycolysis and oxidative phosphorylation facilitating tumor growth reduction.

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CoFe nanowires for remote heating using an alternating magnetic field

A nanowire material for remote, rapid and uniform heating of biological samples.

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Subfield Level Model for Improved Nitrogen Fertilizer Recommendations

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Biodegradable lactose-based hydrogel

A method to produce biodegradable lactose-based hydrogel from lactose-containing dairy waste.

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A TLR-2 stimulatory molecule for use as a vaccine adjuvant

A small molecule that serves as an adjuvant in vaccines through stimulation of the immune receptor, TLR-2

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Delivery of developmental regulators to whole plants for the induction of genetically altered meristematic tissue (Dr. Voytas)

Research out of the Voytas Lab provides a method for the creation of genetically-altered seeds within one generation via the induction of new plant meristems.

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Unique small molecule modulators of GPCRs

Novel small molecules that bind and modulate G-protein coupled receptors (specifically Sigma 1 and 5-HT7) for therapeutic development.

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Antibody based treatment for Type 1 Diabetes

A humanized monoclonal antibody against Serpin B13 to treat Type 1 Diabetes.

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Immunostimulatory conjugates for targeted delivery as adjuvants

Novel vaccine adjuvants composed of TLR7/TLR8 stimulating compounds conjugated to Hyaluronic Acid (HA) to achieve limited systemic exposure

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Cancer preventative for at risk individuals

An approach to prevent cancers through blocking the transcription factor STAT3 that leads to an 80% tumor reduction in a mouse model of disease.

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Plant Biometric Estimation Using 3D Models

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3D Plant Reconstruction and Biometric Measurement

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Trotter or Pacer? Accurate Method to Detect Preferred Gait in Standardbred Horses

A genetic testing method to accurately (>99%) predict gait profile of Standardbred horses around the globe.

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Novel small molecules for chemotherapy sensitization

Novel phenoxyphenyldeazaflavin compounds that sensitize cancer cells to widely used topoisomerase 2 poisons.

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Quality Control Test for Pathogenic Bacteria Contaminated Water

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Patient Controlled Dynamic Therapeutic Compression Tension Garment

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MHC Class II Molecules with Enhanced Co-receptor Affinity

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High Yield Synthesis of Bio-based Acrylic Acid and Acrylate Monomers from Lactic Acid (20180106, Dr. Marc Hillmyer)

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A novel chemotherapy drug with reduced patient side-effects

A novel anti-cancer compound that inhibits translation and induces p53 in a DNA-damage independent manner to cause cell cycle arrest and apoptosis.

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High Ammonia Absorbing Corn Stover Hydrochar for use in Horse Bedding

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Microinjection for Single Cell Gene Manipulation

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Referenceless Nyquist Ghost Correction for Echo Planar Imaging (EPI)

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Segmenting 3D Bone Computed Tomography Data

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Tosedostat (CHR-2797) as a Potential Analgesic

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Engineering Human CD64 Chimeric Receptors for Immune Therapy

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Integrated Traumatic Brain Injury Catheter (iTBI)

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Chewing Simulator Provides Sensory Information

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Real-Time Reporter and Efficient Enzymes for DNA Editing

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Versatile Biocatalyst System for Synthesizing Chemicals, Pharmaceuticals and Food Ingredients

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Optimized Radio Frequency Pulses Generated From Magnetic Resonance User Defined Parameters

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Scan-Specific Machine Learning Reconstruction for MRI

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Sliding Windowed Infinite Fourier Transform (SWIFT)

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MRI and Spectroscopy Multi-part Body Coil

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3D Microscale Isotropic Metamaterials

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Biased Unmatched Bivalent LigandsTargeting Asymmetrically Signaling GPCR Homodimers

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Probes for Biosynthesis of Bacterial Cell Wall

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Unique compounds to treat obesity

Unique compounds are the first-ever to target melanocortin receptor 3 in an effort to treat obesity without increasing blood pressure.

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Increase Signal-to-noise Ratio in Imaging Data

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Bacterial Histidine Kinase Inhibitor

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Faster MRI Acquistion with Motion Robustness

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Tunable Neural Electrodes for MRI-Compatible Brain Signal Recordings

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Biomass Absorbs Phosphates and Phosphate-Containing Herbicide (Organophosphates)

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Myocardial Viability Functional Assessment

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Dynamic Quantification of Myocardial Tissue MRI

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Orthopedic Meniscus Repair Implant, Introducer and Delivery System

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Conformable Dual-mode Ultrasound Transducers for Neuromodulation

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Rationale Design of Inhibitors based on Crystal Structures of ssDNA Bound to APOBEC

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Single Voxel MR Spectroscopy of Human Brain with Automatic Voxel Positioning

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Solar UV-Induced Skin Cancer Inhibitor

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Magnetization Transfer Contrast Preparation

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Multi-modal Neuromodulation Therapy Promotes Sleep

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Pediatric Tracheo-bronchomalacia Stent and Deployment System

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Fluorescence-based Detection of Kinase Allostery for High-throughput Allosteric Inhibitor Discovery

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Mimicked Calcified Annulus Model for Preclinical Assessment of TAVR Devices

From $1500.00
1 licensing option
Motion-Robust Cardiac B1+ Mapping of the Transmit Field

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Imaging Source Distribution from Electromagnetic Signals

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High-voltage, Fully-integrated, High-density Microstimulator with Charge Balancing

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Predicting Crop Yield and Quality Using Canopy Reflectance and LiDAR Sensors

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Simultaneous RF Signal Transmission and Reception in MRI (20160420)

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Neural Recording under Electrical Microstimulation

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Adaptive Immune Response Stimulated with TLR8 and Dual TLR7/TLR8 Agonists

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Black-Blood T1 Myocardial Mapping to Remove Partial Voluming Effects

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PDAC Treatment with High Antiproliferative Activity Against MiaPaca-2

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Lung Biopsy Tool

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Treating Tumors with High Intensity Focused Ultrasound

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Novel inhibitors of HINT1 to treat neuropathic pain and addiction

Small-molecule inhibitors of hHint1 (and their synthesis) for use in basic CNS research and treatment of neuropathic pain and addiction.

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Optimizing Gene Editing in NK Cells for Therapy and Research

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Anti-obesity and Weight Control Drugs Target Melanocortin Receptor

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Porcine B lymphoma cell lines

Three porcine B cell lines (Murtaugh001, Murtaugh002, Murtaugh003) established by 3 rounds of limiting dilution from splenic and subiliac lymph node lymphomas.

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Weight Management Drugs using Selective Melanocortin Ligands

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Smart Clothing with Dynamically Controlled Compression

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Engineered enzymes to disrupt bacterial communication and reduce virulence

Engineered enzymes that inhibit bacterial virulence factors by breaking down bacterial communication molecules.

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Engineered enzymes to disrupt and prevent biofilms

Engineered enzymes that inhibit hazardous and infectious biofilms by breaking down bacterial communication molecules.

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Environmentally-friendly, enzymatic anticorrosion and antifouling coating

A method to reduce microbial-caused corrosion and biofouling through the use of an enzymatic coating to disrupt bacterial communication

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Multiplex Plant Gene Targeting through Homologous Recombination (20160266, Dr. Daniel Voytas)

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Designing 2D and 3D Adiabatic Pulses

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Neuromodulator for Simultaneous Stimulation and Signal Reception

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Colorimetric Assay for Microbial Screening

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Improved Craniotome to Prevent Dural Tear

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Efficient release of affinity-captured cells

A method to effectively release affinity-captured cells.

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Efficient Bio-intensive Gardening Tool Design

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Developing Highly Specific Monoclonal Antibodies to Peptide in the Context of MHC II

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Nonsurgical Method for Restoring Tooth Enamel

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Peptide Activation of T Cells for Cancer Immunotherapy

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Radiofrequency Antenna Array with Electric Dipole and Loop Elements

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Biomarker for Diagnosis of Aggressive Breast Cancer

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Warming of Cryopreserved Biomaterials using Laser Assisted Gold Nanorods

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Improved Pertussis Vaccine

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0 licensing option
Bee Squad Varroa Mite Testing Kit

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0 licensing option
Algorithm for Discovering Genetic Interactions in Genome-Wide Association Studies (BridGE)

FREE OF CHARGE
1 licensing option
Hydrophobic Surfaces for Tooth Tissues

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0 licensing option
High Quality Mosaics from UAV Obtained Images

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0 licensing option
Automated Detection of Nitrogen Deficiency in Corn

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0 licensing option
Glyphosate Resistance from Altered EPSPS Plant Genes (20160028, Dr. Daniel Voytas)

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Adaptive Refocusing of Ultrasound Arrays Using Synthetic Aperture Imaging Data

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Live Attenuated Viral Vaccines

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Nucleic Acid Delivery to the Liver for Hemophilia and Lysosomal Storage Disease Treatment (20150339, Dr. Reineke)

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Catheter System with Guidewire Compartmentalization (20150223, Dr. Rumi Faizer)

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0 licensing option
HerdIn:Form(er): Mobile Questionnaire for Livestock Epidemiology Research (20150194, Dr. Andres Perez)

FREE OF CHARGE
1 licensing option
Lower Extremity Edema Monitor (20150192, Dr. Rajesh Rajamani)

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0 licensing option
Deep Brain Stimulation Using Magnetic Brain Array (20150177, Dr. Jian-Ping Wang)

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0 licensing option
Improved Deep Brain Stimulation Target Selectivity (20150170, Dr. Shalom Michaeli)

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Increased efficiency of CRISPR-Cas9 genome editing (20150143, Dr. Wendy Gordon)

An approach that increases the efficiency of CRISPR/Cas-9 genome editing 30-fold by fusing Cas9 to an HUH endonuclease tethered to the desired donor DNA.

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0 licensing option
Improved MRI Quality with Gradient Modulation Pulse Sequence (20150133, Dr. Kobayashi, Dr. Garwood)

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0 licensing option
Acousto-electromagnetic Imaging of the Brain (20150126, Dr. Bin He)

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Phytate Extraction from Corn Ethanol Coproducts (20150123, Dr. Bo Hu)

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0 licensing option
HILAGE: Haploid Inducer Line for Accelerated Genome Editing (20150117, Dr. Robert Stupar)

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Biodiesel from Scum Oil and Waste Oil (20150113, Dr. Roger Ruan)

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0 licensing option
Time Efficient Arterial Spin Labeling Imaging with Segmented Multiband-acquisition (20150097, Dr. Greg Metzger)

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0 licensing option
Cold Hardy Itasca Grape Variety

From $1000.00
2 licensing options
Improved MRI Method Uses Temperature Rise Contraints (20150061, Dr. Moortele)

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0 licensing option
LJ-1000 Apple Variety (20150018, Dr. Bedford)

From $1000.00
1 licensing option
Therapeutic compound for chronic inflammatory pain without dependence or tolerance (20140357, Dr. Philip Portoghese)

An analgesic compound without side effects that relieves chronic pain associated with arthritis, sickle cell disease, chemotherapy, AIDs and inflammation.

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0 licensing option
Biofertilizer from Genetically-modified Azotobacter vinelandii (20140348, Dr. Brett Barney)

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Mapping Prostate Cancer from Multi-parametric MRI with Improved Predictive Models (20140287, Dr. Greg Metzger)

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High Strength Lignin Based Plastics (20140254, Dr. Simo Sarkanen)

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0 licensing option
In-vivo MRI Radiofrequency Pulses Robust against Respiration Induced Errors (20140236, Dr. Kamil Ugurbil)

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Microbiome Profiling Techninque for Improving Commercial Turkey Production (20140230, Dr. Timothy Johnson)

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0 licensing option
Physocarpus Opulifolius “Center Glow Ninebark” (20140201, Dr. Harold Pellett)

From $1000.00
2 licensing options
Multi-band SWIFT Improves MRI (20140121, Dr. Idiyatullin, Dr. Garwood)

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0 licensing option
Generalized Multiband Slice Accelerated Imaging (20140093, Dr. Dingxin Wang)

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Bovine Tuberculosis Screening (20140058, Dr. Srinand Sreevatsan)

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Reduced-power SWIFT Magnetic Resonance Imaging (20140052, Dr. Jinjin Zhang, Dr. Garwood)

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Precision Agriculture Drone Algorithms (20140013, Dr. Volkan Isler)

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Wheat Variety Selection Tool for Wheat Farming (20140006, Dr. Jochum Wiersma)

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0 licensing option
Conferring Plant Resistance to Geminiviruses using CRISPR/Cas Systems (20130311, Dr. Daniel Voytas)

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Hay Prices per Ton Calculator App (20130300, Dr. Krishona Martinson)

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Healthy Horse App Calculates Weight (20130294, Dr. Krishona Martinson)

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Canine Brain MRI Atlas (20130233, Dr. Thomas Fletcher)

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Multislice Multiband Excitation with Parallel Transmission for B1 Homogenization and Power Reduction (20130170)

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IV Line Lifting Device (20130136, Dr. Mary Hooke)

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Intraoral Dental MRI Coil (20130110, Dr. Michael Garwood)

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MRI Signal Separation using Iterative Calibration (20130079, Dr. Kamil Ugurbil)

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Enhancing Cardiac Function Using Short Protein Inhibiting DNAs and RNAs (20120271, Dr. Michael Bowser)

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0 licensing option
Immunotherapy for Dogs with Increased Immune Response (20120263, Dr. John Ohlfest)

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0 licensing option
Simultaneous RF Transmit and Receive in MRI Coils (20120123, Dr. Tommy Vaughan)

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0 licensing option
MRI Coil Amplifiers (20120122, Dr. Tommy Vaughan)

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0 licensing option
Human Whole-Body Imaging at 7T (20120120, Dr. Tommy Vaughan)

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Electrical Auto-tuning for Ultra-High-Field MRI RF Coils (20120119, Dr. Tommy Vaughan)

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0 licensing option
MRI Method Reduces Peak Power for Multiband Images (20120077, Dr. Kamil Ugurbil)

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Synchronized Multi-Modal Tinnitus Therapy (20120070, Dr. Hubert Lim)

A non-invasive or minimally-invasive method for the suppression of tinnitus using synchronized brain stimulation.

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0 licensing option
Canine Lymphoma Prognostic Classification (20120065, Dr. Jaime Modiano)

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0 licensing option
Beam Steering Resonance along a Spatiotemporal Trajectory for MRI (20120060, Dr. Michael Garwood)

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0 licensing option
MRI Pulse Sequence: Steering Resonance over the Object (20120049, Dr. Michael Garwood)

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0 licensing option
Faster Functional and Diffusion MRI of the Brain (20110139, Dr. Kamil Ugurbil)

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0 licensing option
Lower Specific Absorption Rate for Multiband MRI (20110093, Dr. Kamil Ugurbil)

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0 licensing option
Faster Whole Brain Imaging (20110092, Dr. Kamil Ugurbil)

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0 licensing option
Generation of NK and Innate Lymphoid Cells from human stem cells (20110085, Dr. Michael Verneris)

Drs. Verneris, Miller and Blazar developed a method to create large numbers of Natural Killer cells and Innate Lymphoid Cells from hematopoietic stem cells.

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0 licensing option
Minnesota First Kiss™ Apple (MN55 Variety) (20110037, Dr. David Bedford)

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1 licensing option
Insulin Producing Cells from Pluripotent Stem Cells (20100245)

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0 licensing option
Ultrasound System for Characterization and Image-guided Therapy of Blood Vessel Diseases (20100155)

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0 licensing option
Tracking Deformation of Organs during Minimally Invasive Surgery

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0 licensing option