Remedy for Heart Failure with Preserved Ejection Fraction

Technology No. 20170160
IP Status: Pending US Patent; Application #: 15/899,174

Increases volume of left ventricle

A manufacturing and delivery process design provides a medical device that can remedy heart failure with preserved ejection fraction. The device, a three-dimensional textile structure manufactured with a superelastic wire, is delivered and attached by catheter to the left ventricle of the heart, where the superelastic textile structure provides a radial outward force on the left ventricle, increasing the volume of the left ventricle.

Preserved Ejection Fraction Clinical Treatment

Currently, there are no clinical interventions available to treat heart failure with preserved ejection fraction, a condition where the left ventricle of the heart does not expand properly, leading to a decrease in filling volume of the left ventricle, an increase in pressure in the left ventricle and left atrium, and pulmonary edema. Some pharmacological interventions showed early promise but later failed during clinical testing, and one device remedies the symptoms but does not address the underlying problems. This new technology provides a clinical intervention to treat heart failure with preserved ejection fraction.

BENEFITS AND FEATURES:

  • Treats heart failure with preserved ejection fraction
  • Superelastic textile structure provides radial outward force to ventricle
  • Three-dimensional textile structure
  • Delivered and attached by catheter

APPLICATIONS:

  • Remedy for heart failure with preserved ejection fraction
  • Designing three-dimensional textile structures to provide desired mechanical performance

Phase of Development - Conceptual model and early design specifications.

Researchers
Andrew Khair, PhD
Alumni Innovation Fellow, Medical Devices Center
External Link (www.mdc.umn.edu)
Julianna Abel, PhD
Assistant Professor, Mechanical Engineering
External Link (www.me.umn.edu)

Publications
Hierarchical architecture of active knits
Smart Materials and Structures, 1 November 2013, Vol 22, Num 12

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