Wearable laryngeal vibration system for Spasmodic Dysphonia (20170400)
A non-invasive neuromodulation device and method for the treatment of spasmodic dysphonia.
Pharmacological agents to prevent recurrent C. diff infection (20150362)
Cholic and bile acid derivatives that inhibit Clostridium difficile spore germination to prevent or treat C. diff infection.
A method to genetically engineer monocytes (20180236)
The first and only method available to create genetically modified CD14+ monocytes for use in research or therapy.
A streamlined method to isolate Fibroadipogenic progenitor cells from muscle (2020-195)
A method to isolate fibroadipogenic progenitor cells (FAPs) based on the presence of a single surface marker (CD73).
PEGylated Fibrin Biomatrix for Treatment of Acute Myocardial Infarction
Genetic Modification of Endostatin: An Anti-Angiogenic Therapeutic
More Stable and Potent Cyclic ADP-Ribose Analogs
Treating Neurodegenerative Diseases with Nicotine Receptor Ligands
Modified Sleeping Beauty Transposon Gene Transfer System
Cell Cryopreservation for Lymphocytes Improves Hematopietic Cell Survival
Novel process to obtain large quantities of primary cells for transplantation
A method to isolate large quantities of high quality primary cells for therapeutic transplantation through freezing and thawing organs, including organs typically considered suboptimal for donation.
Dental stem cells to treat spinal cord injury
A method of treating nervous tissue damage using dental pulp stem cells that leads to neuro-regeneration with a high safety profile and low probability of patient rejection.
CoFe nanowires for remote heating using an alternating magnetic field
A nanowire material for remote, rapid and uniform heating of biological samples.
Novel small molecules for chemotherapy sensitization
Novel phenoxyphenyldeazaflavin compounds that sensitize cancer cells to widely used topoisomerase 2 poisons.
MHC Class II Molecules with Enhanced Co-receptor Affinity
Microinjection for Single Cell Gene Manipulation
Tosedostat (CHR-2797) as a Potential Analgesic
Engineering Human CD64 Chimeric Receptors for Immune Therapy
Real-Time Reporter and Efficient Enzymes for DNA Editing
Rationale Design of Inhibitors based on Crystal Structures of ssDNA Bound to APOBEC
Optimizing Gene Editing in NK Cells for Therapy and Research
Efficient release of affinity-captured cells
A method to effectively release affinity-captured cells.
Peptide Activation of T Cells for Cancer Immunotherapy
Increased efficiency of CRISPR-Cas9 genome editing (20150143, Dr. Wendy Gordon)
An approach that increases the efficiency of CRISPR/Cas-9 genome editing 30-fold by fusing Cas9 to an HUH endonuclease tethered to the desired donor DNA.
Cryopreservation without Dimethyl Sulfoxide (20140289, Dr. Allison Hubel)
Bacterial Biofilms Targeted with Microbial Drone Therapeutics (20140281, Dr. Christine Salomon)
Mesoporous Silica-coated Iron Oxide Nanoparticle (20140249, Dr. Christy Haynes)
ssDNA Amphiphile Self-Assembly Forms DNA Nanotubes (20140227, Dr. Efie Kokkoli)
Drug Delivery System with Precise Drug Release (20140084, Dr. Joseph Zasadzinski)
Small RNA Amplification and Library Preparation (20140020, Dr. Subree Subramanian)
Cerebral Amyloid Angiopathy and Alzheimer’s Disease Diagnosis and Treatment (20130341, Dr. Karunya Kandimalla)
Blood Sugar Regulation with D-serine (20130320, Dr. Amber Lockridge)
Reagent for Dual Protein Labeling (20130255, Dr. Mark Distefano)
Immunosuppression Augmented by CD200 Derived Peptide (20130229, Dr. Michael Olin)
Molecular Probe Measures Nucleosides and Differentiation of ATP and ADP (20120272, Dr. Valerie Pierre)
Enhancing Cardiac Function Using Short Protein Inhibiting DNAs and RNAs (20120271, Dr. Michael Bowser)
Immunotherapy for Dogs with Increased Immune Response (20120263, Dr. John Ohlfest)
Controlled Drug Release with Drug Delivery System (20120102, Dr. Chun Wang)
Nanoparticle Chemotherapy with Anticancer Prodrugs (20110152, Dr. Thomas Hoye)
Alzheimer’s and Neurodegenerative Disease Treatment (20110150, Dr. Robert Vince)
Generation of NK and Innate Lymphoid Cells from human stem cells (20110085, Dr. Michael Verneris)
Drs. Verneris, Miller and Blazar developed a method to create large numbers of Natural Killer cells and Innate Lymphoid Cells from hematopoietic stem cells.