3D vector field-guided toolpathing for 3D bioprinting
A novel software suite for converting three-dimensional vector field data into machine code for manufacturing.
Technology No. 2025-247, 2023-113
IP Status: Copyrighted; US Patent Pending, Application No. 18/769,027
The software suite is fully scripted, documented, and tested on a limited set of ex vivo human cardiac data.
Applications
- Disease modeling
- Drug development
- Patient treatment
Technology Overview
Researchers at the University of Minnesota have developed a novel software suite that intakes either fiber tractography data or Diffusion Tensor Magnetic Resonance Imaging (DT-MRI) and produces G-code, the type of machine code used by most 3D printers. The Nonplanar, Architecture-Aligned Toolpathing for In Vitro 3D bioprinting (NAATIV3) framework processes DT-MRI data to map tissue fibers, reduce them to a representative subset, remove conflicting fibers, select a printing sequence, and output a G-code file.
Phase of Development
TRL: 4-5The software suite is fully scripted, documented, and tested on a limited set of ex vivo human cardiac data.
Researchers
- Michael McAlpine, PhD Kuhrmeyer Family Chair Professor, Department of Mechanical Engineering
- Angela Panoskaltsis-Mortari, PhD Professor, Department of Pediatrics
- Ravi Janardan, PhD Professor, Department of Computer Science & Engineering
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