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z08158 – A mouse model for the study of human brain tumors in a variety of ways, such as generation of "humanized" models for high throughput drug screening and candidate gene validation with exceptional speed and flexibility. The Sleeping Beauty transposable elements are used to achieve chromosomal integration of human oncogenes into endogenous brain cells of immune-competent mice.... Read More
z09100 – This transgenic mouse model can help researchers understand the fundamental biology behind iron deficiency's effects on the brain. It was created by crossing targeted Slc11a2 flox/flox mice in a 129 J1 background strain (20) with CaMKIIα−cre (L7ag#13 line (21)) transgenic mice in a C57BL/6J background to generate double mutant, hippocampal neuron specific knockout of Slc11a2... Read More
20110048 – BAC transgenic mouse that expresses GFP when stimulated through the T or B cell antigen receptor has many applications for basic research on the immune system, infectious disease, autoimmune disease, transplantation, vaccination, and immunotherapy for cancer. It will also be useful in screening compounds designed to activate or inhibit T cell receptor or B cell receptor activation in... Read More
20110168 – Collection of three canine melanoma cell lines for research purposes. Melanoma is the most dangerous type of skin cancer, and is the leading cause of death from skin disease. Melanoma is not the most common form of skin cancer, but rates are steadily increasing. This cell line can be used as a research tool for cancer study, including; therapeutic development, mechanism studies, tumor... Read More
20120137 – This clone is a sub-clone of the well-defined DF-1 cells and is able to produce higher Marek's Disease Virus titers compared to the parental cell line. Marek's Disease Virus is a major poultry pathogen for which there is no known cure. The poultry industry needs a high titer vaccine for Marek's Disease Virus from a well characterized master seed stock in order to vaccinate billions of... Read More
cmrr – The Center for Magnetic Resonance Research (CMRR) at the University of Minnesota develops magnetic resonance imaging, spectroscopy methodologies and instrumentation to non-invasively aquire structural, functional and biochemical information from humans. These capabilities are used to study the function of organs in healthy and diseased states. CMRR has developed pulse sequence software that... Read More
20100059 – The STAT5b-CA x pax5+/- leukemic cell line grows in the presence of interleukin-7. Withdrawal of IL7 results in cell death. We have also treated the STAT5b-CA x pax5+/- cell line with the histone deacetylase inhibitor apicidin. Cell line can be used to identify genes required for transformation and survival of the leukemic cells. Likewise, both the cell line and mouse model can be used to... Read More
z04191 – WK-1 is an immortalized chicken embryo fibroblast cell line. It demonstrates very rapid growth and is non-tumorigenic. It can be used for the investigation of avian cellular mechanisms related to cell proliferation and for possible virus propagation. It can also serve as a model for characterizing endogenous growth stimulating growth factors.
20100020 – Biologically active agents can be detected using a giant magnetoresistor (GMR) sensor and magnetic nanoparticle based coloring. Current optical fluorescence based techniques have low signal to noise and require bulky and expensive equipment. The magnetic biomedical sensor provides a low cost, high throughput, portable and high signal to noise method of detection. The magnetic signal can... Read More
20110008 – Copper, Zinc, Tin and Sulfide (CZTS) thin films are an exciting development in solar cell technology. CZTS uses abundant materials instead of rare earth elements such as indium in copper indium gallium selenide (CIGS) solar cells and tellurium in cadmium telluride (CdTe) solar cells. CZTS solar cells are expected to give similar performance characteristics to CIGS and CdTe. ** View... Read More
20110010 – The Beating Heart Simulator Kit was designed for medical students studying the evaluation and diagnosis of heart arrhythmias. The heart model provides a comprehensive learning environment by utilizing multiple forms of stimuli while maintaining an affordable price for students. The affordable price allows for broader distribution and can increase learning by providing students with... Read More
z04203 – Tooth Explorer is a three dimensional dental software program designed to teach oral anatomy in a highly efficient digital environment. This program provides dentistry students with an interactive, three-dimensional dental library of 32 individual adult teeth. Students are able to engage in self-paced learning by rotating and identifying significant features of individual, anatomically... Read More
20110025 – The Digital Pathology Virtual Microscope Slides allow medical students and allied health professionals to access hematology microscope slides through an online database for distance learning and enhanced curriculum delivery. The Digital Pathology Virtual Microscope Slide database is the only database that offers a high quality resolution of 83X oil immersion, which is necessary for the... Read More
z09085a – A fabrication method to obtain ultra-smooth pure metal films with a variety of nanometer sized structural features including grooves, bumps, pyramids, ridges, and holes for sensor and plasmonic applications has been developed. It is a simple, high throughput process that is highly reproducible and produces fewer surface imperfections than other processes. The devices produced using... Read More
z08118 – The principal goal of the electronic Primary Care Research Network (ePCRN) is to enable the development of an electronic infrastructure to support clinical research activities in primary care practice-based medical research networks (PBRNs). ePCRN is a set of software tools that can connect practitioners within a medical organization and has the potential to connect practitioners with... Read More
z09208 – Researchers at the University of Minnesota have compiled a library of 1,600 analgesics consisting of several classes of molecules and the synthetic intermediates used to create them by chemical reactions. The chemical compounds detailed in the library fall into the following broad categories: agonists, which stimulate a response from cells, antagonists, which obtain a desired outcome... Read More
ndsr87072 – Nutrition Data System for Research (NDSR) is a Windows-based nutrition analysis program designed for the collection and analyses of 24-hour dietary recalls, food records, menus, and recipes. Calculation of nutrient intake occur immediately providing data per ingredient, food, meal, and day in report and analysis file formats. The software includes a dietary supplement assessment module so... Read More
z01136 – Histology is the study of the structure and function of the cells, tissue and organs of the human anatomy as viewed through a microscope. The Histology Time software helps students learn anatomy and cell biology through a computer-based histology atlas of cells, tissues, and organs. The database contains more than 5,000 light microscope images organized into nineteen chapters covering... Read More
z01192 – The brain anatomy software package, NeuroTime®, helps students study neuroanatomy, learn the central nervous system structures and interpret brain MRI images (magnetic resonance imaging) in an interactive environment. The software includes high quality images of intact and dissected gross specimens of the central nervous system, whole brain sections and brain MRI images. Information is... Read More
97145 – The Probability of Repeated Admission (Pra) elder health assessment survey identifies senior citizens who are at high risk of repeated hospital admissions and extensive use of health care services. The early prediction of hospital readmission risk helps those patients receive better medical attention, which will result in better health for them, and lower expenses for hospitals and... Read More
z06083 – Researchers have identified a high-risk genetic combination of DNA sequences, called a haplotype, for systemic lupus erythmatosus (SLE). Systemic lupus erythmatosus is the most common form of lupus and the most serious. Lupus is a chronic inflammatory disease in which the body's immune system attacks its own tissues and organs. There is currently no cure for lupus, but the disease is... Read More
95149 – Advances in vaccine development have led to a renewed interest in their use for prevention and treatment of diseases such as HPV, cancer, and communicable disease. Ensuring that new vaccines are not only effective, but also safe and free of contaminants including retroviruses is one of the major challenges facing vaccine makers. Retrovirus contamination in a vaccine is a serious concern... Read More
20090011 – The Sarcoma miRNA Expression Database (S-MED) provides comprehensive information about microRNA expression patterns in sarcomas and other relevant cancer tissue types, helping the diagnosis, classification, prognosis, and treatment of malignant tumors. MicroRNAs (miRNAs), a class of small RNAs regulating expressed genes in human sarcomas, can assist in the development of cancer... Read More
z02025 – The bioreactor creates "designer organisms" that utilize renewable resources to produce cellulosic fuels, cellulosic chemicals, and cellulosic ethanol. Microbe growing bioreactors are vital systems in the development of these organisms that must be able to consume a variety of feedstocks, survive the toxic by-products of the production process, and must withstand a variety of... Read More
z07108 – Virtual reality, laparoscopic, surgical training, software improves the quality of training for surgical procedures by providing users with real-time virtual reality simulations. The computer aided surgical simulation technology provides an interactive learning environment with high-fidelity models that use real tissue properties with realistic textures for enhanced laparoscopic surgical... Read More
z08194 – SALSA is a software program that automates quantitative analysis of spontaneous speech and language for use in assessing neuropsychological cognitive impairment caused by a variety of factors. SALSA speech assessment software analyzes spontaneous speech samples produced in response to several types of stimuli including picture descriptions, recall of a story, or a spontaneous... Read More
monoclonal-antibodies – Monoclonal and polyclonal antibodies are antigen-specific targeting proteins useful as important research tools in the fields of immunology, cell biology, biochemistry, molecular biology, neurology, and medicine. It is possible to create monoclonal and polyclonal antibodies to nearly any biologically-relevant substance, which can then be identified and/or purified using common laboratory... Read More
94019 – The content of the Minnesota Living with Heart Failure questionnaire (MLHFQ) was selected to be representative of the ways heart failure and treatments can affect the key physical, emotional, social and mental dimensions of quality of life without being too long to administer during clinical trials or practice. Responses of patients with heart failure to the Sickness Impact... Read More
