Office for Technology Commercialization

On-Demand Production of Peracetic Acid

Technology #z05117

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Peracetic AcidBleachingPeracid
Romas J. Kazlauskas , PhD
Professor, Department of Biochemistry, Molecular Biology, and Biophysics, College of Biological Sciences
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Managed By
Larry Micek
Technology Licensing Officer 612-624-9568
Patent Protection
US Patent 7,384,787
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Peraceitc Acid Term Sheet [PDF]

Limiting Need to Store and Handle Peracetic Acid

A method using an enzymatic biocatalyst can generate peracids. The process involves adding perhydrolase activity to an esterase enzyme, and optimizing the enzyme activity through targeted mutations.  Perhydrolase enzymes form peracetic acid from acetic acid and hydrogen peroxide. Generation of peracids via enzyme biocatalysis allows producing disinfection agents on demand, limiting the need to store and handle highly explosive peracetic acid.

MN-IP Try and Buy
  • Trial fee is $5,000 for a six month license
  • $30,000 conversion fee (TRY to BUY)
  • No patent costs
  • Royalty rate of 3% (2% for MN company)
  • Royalty free for first $1M in sales

** View the Term Sheet **
** Contact Larry Micek for specific details. **

Peracid Used for Disinfection

Peracids are potent chemicals that have long been used for disinfection in industry, such as disinfection of animal carcasses in the food industry. One of the challenges with using peracids is that their production via chemical routes involves a formulation that is strongly acidic, and the peracids are extremely unstable in solution after they are created.


  • Able to create peracetic acid on-demand and in solution, which avoid the storage hazards associated with peracetic acid
  • Can apply the selection method to tailor enzymes to exhibit selectivity for certain functional groups

Phase of Development Demonstrated for one enzyme