Office for Technology Commercialization

Biological Imaging using a CMOS or CCD Image Sensor

Technology #z01174

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Biological ImagingDNA FluorescenceBiological Analysis
Martin Blumenfeld, PhD
Emeritus faculty, Genetics, Cell Biology and Development Department, College of Biological Sciences
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Doug Franz
Technology Licensing Officer 612-624-0869
Patent Protection
US Patent 7,145,645

DNA Fluorescence Detection

A method has been developed to acquire digital images and maps of biological samples using an electronic light detector array, for example a CCD or CMOS image sensor. The biological sample may include biological holding structures such as a DNA spot array on a DNA chip and protein bands in a 2D gel. The array allows imaging methods such as fluorescence detection from a biological sample to be analyzed.

MN-IP Try and Buy
  • Trial period up to 18 months. $5000/6 months.
  • Fee waived if MN operating company or if sponsoring $50,000+ in research.
  • Exclusive license for a $20,000 conversion payment.
  • No U.S. patent expenses.
  • 1.5% Royalty (1.0% for MN companies) after $1 million in product sales.

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This technology is also available for licensing as part of the Biological Imaging Portfolio.

Low Cost Biological Sample Analysis

Current methods of biological sample imaging involve placing a DNA chip on a microscope and moving the stage into focus. Such equipment is expensive and generally requires a high degree of skill and training to operate and maintenance to keep operational. The described technology allows for a less expensive, lower maintenance alternative spot detection method and apparatus for biological sample analysis.


  • Simpler biological imaging using an electronic light detector.
  • Less expensive and less maintenance than current technology.
  • Typical analysis includes DNA Chips, DNA spots and fluorescence analysis

Phase of Development Proof of concept. Demonstrated in laboratory.