Ursodiol Derivatives can Reduce Apoptosis in Cells
Methods of utilizing ursodiol and its
derivatives to limit cell apoptosis have been developed and can inhibit
programmed cell death originating from multiple causes in various body
systems. This invention discloses methods to inhibit apoptosis in
autoimmune diseases, cardio and cerebrovascular diseases, and
neurodegenerative diseases. Ursodiol has also been shown to maintain
viability, thereby decreasing the need for more serious interventions.
Overall the technology can assist in the treatment of various diseases
and the reduction of disease symptoms.
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Programmed Cell Death in Disease and Treatments
Apoptosis is the process of programmed cell death in an organism. Apoptosis plays a role in many diseases and the treatments for many diseases, often contributing to the disease severity or hindering the success of treatments. For example, apoptosis is believed to be the cause for the symptoms associated with many liver diseases, it inhibits success of neural replacement therapies for Parkinson's, and it hinders recovery following ischemic stroke. A need exists for a method to prevent undesired apoptosis in humans.
BENEFITS OF METHODS OF LIMITING APOPTOSIS:
- Decreases severity of symptoms associated with many diseases
- Maintains viability which decreases the need for more serious interventions
- Applications in various diseases and body symptoms- including neurodegenerative, cardiovascular, cerebrovascular, and autoimmune diseases