Office for Technology Commercialization

3D printed bionic skull for multimodal neural sensing

Technology #2019-293

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Suhasa Kodandaramaiah, PhD
Benjamin Mayhugh Assistant Professor, Mechanical Engineering
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Michael McAlpine, PhD
Kuhrmeyer Family Chair Professor, Mechanical Engineering
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Managed By
Doug Franz
Technology Licensing Officer 612-624-0869
Patent Protection

Provisional Patent Application Filed


  • Neurotechnology / Neuroscience

Technology Overview

Practical technologies that enable simultaneous mapping of neuronal activities from large brain volumes at cellular resolution currently do not exist. Researchers at the University of Minnesota have conceptualized a transparent bionic skull for volumetric mapping of single-cell neuronal activities of up to a 45 sq mm area in cortex of a freely moving mouse at physiologically relevant temporal resolution. The bionic skull design includes optical instrumentation for high resolution imaging and sensors to track ultra-fast genetically encoded voltage indicators.

Phase of Development

TRL: 2-3
Concept. Prototype under development.

Desired Partnerships

This technology is now available for:

  • License
  • Sponsored research
  • Co-development
Please contact Doug Franz to share your business’ needs and learn more.