Office for Technology Commercialization
http://www.research.umn.edu/techcomm
612-624-0550

Remedy for Heart Failure with Preserved Ejection Fraction

Technology #20170160

Questions about this technology? Ask a Technology Manager

Download Printable PDF

Image Gallery
Heart
Categories
Researchers
Andrew Khair, PhD
Alumni Innovation Fellow, Medical Devices Center
External Link (www.mdc.umn.edu)
Julianna Abel, PhD
Assistant Professor, Mechanical Engineering
External Link (www.me.umn.edu)
Managed By
Kevin Anderson
Technology Licensing Officer 612-624-8293
Patent Protection

Provisional Patent Application Filed
Publications
Hierarchical architecture of active knits
Smart Materials and Structures, 1 November 2013, Vol 22, Num 12

Increases volume of left ventricle

A manufacturing and delivery process design provides a medical device that can remedy heart failure with preserved ejection fraction. The device, a three-dimensional textile structure manufactured with a superelastic wire, is delivered and attached by catheter to the left ventricle of the heart, where the superelastic textile structure provides a radial outward force on the left ventricle, increasing the volume of the left ventricle.

Preserved Ejection Fraction Clinical Treatment

Currently, there are no clinical interventions available to treat heart failure with preserved ejection fraction, a condition where the left ventricle of the heart does not expand properly, leading to a decrease in filling volume of the left ventricle, an increase in pressure in the left ventricle and left atrium, and pulmonary edema. Some pharmacological interventions showed early promise but later failed during clinical testing, and one device remedies the symptoms but does not address the underlying problems. This new technology provides a clinical intervention to treat heart failure with preserved ejection fraction.

BENEFITS AND FEATURES:

  • Treats heart failure with preserved ejection fraction
  • Superelastic textile structure provides radial outward force to ventricle
  • Three-dimensional textile structure
  • Delivered and attached by catheter

APPLICATIONS:

  • Remedy for heart failure with preserved ejection fraction
  • Designing three-dimensional textile structures to provide desired mechanical performance

Phase of Development - Conceptual model and early design specifications.

Interested in Licensing?
The University relies on industry partners to scale up technologies to large enough production capacity for commercial purposes. The license is available for this technology and would be for the sale, manufacture or use of products claimed by the issued patents. Please contact Kevin Anderson to share your business needs and technical interest in this technology and if you are interested in licensing the technology for further research and development.