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Improved Multi-Band Magnetic Resonance Imaging (MRI)

Technology #20140303

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Image Gallery
MB imaging slice groups/MB RF pulse component index for MB-EPI in (pseudo-continuous arterial spin labeling) pCASL perfusion imagingTop: total leakage factor (TLF); Middle: LF evaluation; Bottom: measured TLF mapsExample of spatially shifting leakage contaminations from eyeballs (indicated by red circles) due to the application of different PE shift factors
Categories
Researchers
Kamil Ugurbil, PhD
Professor, Department of Radiology, Center for Magnetic Resonance Research
External Link (www.radiology.umn.edu)
Xiufeng Li, PhD
Assistant Professor, Department of Radiology, Center for Magnetic Resonance Research
External Link (www.radiology.umn.edu)
Greg Metzger, PhD
Associate Professor, Department of Radiology, Center for Magnetic Resonance Research
External Link (www.radiology.umn.edu)
Steen Moeller, PhD
Assistant Professor, Department of Radiology, Center for Magnetic Resonance Research
External Link (www.radiology.umn.edu)
Dingxin Wang, PhD
Siemens Medical Solutions
Vibhas Deshpande, PhD
Siemens Medical Solutions
Managed By
Kevin Nickels
Technology Licensing Officer 612-625-7289
Patent Protection
US Patent 10,061,005
Publications
NoneTheoretical and experimental evaluation of multi-band EPI for high-resolution whole brain pCASL Imaging
NeuroImage, Volume 106, 1 February 2015, Pages 170-181

Optimizes and improves MB imaging for quantitative imaging

Three new multi-band (MB) imaging methods for MRI adaptively optimize and improve MB imaging performance and quality and increase its flexibility. These approaches can be widely applied to any MB imaging based method.

  • Adaptive MB Imaging (AMI). Adaptively applied RF (radio frequency) pulses, imaging acquisition and reconstruction configurations to optimal performance for a given acquisition.
  • Total Leakage Factor (TLF). To better assess leakage contamination, TLF is a novel acquisition specific metric. 
  • Leakage Evaluation via Acquired Dummy Slices (LEADS). A novel acquisition strategy for measuring TLF.

Applies multiple imaging acquisition and reconstruction parameters

Traditional MB imaging uses only one set of fixed parameters for both imaging acquisition and reconstruction, a practice that limits the performance and flexibility of MB imaging. This new adaptive MB imaging (AMI) technology overcomes such limitations. This approach applies multiple imaging acquisition and reconstruction controlling factors (based on different targeted organs) and improves existing MB imaging by offering more flexibility, optimal performance and improved imaging quality.

Phase of Development

  • Pilot scale demonstration.

Benefits

  • Adaptively optimizes and improves MB imaging performance and quality
  • Increases MB imaging flexibility

Features

  • Three novel MB imaging approaches
  • Adaptively applies RF pulses, imaging acquisition and reconstruction configurations
  • Evaluates leakage contamination

Applications

  • Magnetic Resonance Imaging (MRI)
  • MRI scanners
  • Multi-band (MB) imaging


Interested in Licensing?
The University relies on industry partners to further develop and ultimately commercialize this technology. The license is for the sale, manufacture or use of products claimed by the patents. Please contact Kevin Nickels to share your business needs and licensing and technical interests in this technology.